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MGI:Ric8

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ric8 ( synonyms: RIC-8, synembryn )
Protein Name(s) resistance to inhibitors of cholinesterase 8 homolog (C. elegans),
External Links
MGI MGI:2141866

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001701

in utero embryonic development

MGI:MGI:3692154
PMID:16221497[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0001944

vasculature development

MGI:MGI:4849883
PMID:21069829[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0001965

G-protein alpha-subunit binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q80ZG1

F

From MGI

GO:0001965

G-protein alpha-subunit binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NVN3

F

From MGI

GO:0001965

G-protein alpha-subunit binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001093990

F

From MGI

GO:0005085

guanyl-nucleotide exchange factor activity

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q80ZG1

F

From MGI

GO:0005085

guanyl-nucleotide exchange factor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001093990

F

From MGI

GO:0005096

GTPase activator activity

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q80ZG1

F

From MGI

GO:0005096

GTPase activator activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001093990

F

From MGI

GO:0005515

protein binding

MGI:MGI:3759160
PMID:17593019[3]

IPI: Inferred from Physical Interaction

UniProtKB:P84309

F

From MGI

GO:0005622

intracellular

MGI:MGI:3759160
PMID:17593019[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005624

membrane fraction

MGI:MGI:3759160
PMID:17593019[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001093990

C

From MGI

GO:0005829

cytosol

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NVN3

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NVN3

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001093990

C

From MGI

GO:0007193

inhibition of adenylate cyclase activity by G-protein signaling pathway

MGI:MGI:3759160
PMID:17593019[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007369

gastrulation

MGI:MGI:4849883
PMID:21069829[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0008277

regulation of G-protein coupled receptor protein signaling pathway

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NVN3

P

From MGI

GO:0008542

visual learning

MGI:MGI:3692154
PMID:16221497[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0009416

response to light stimulus

MGI:MGI:3692154
PMID:16221497[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0042074

cell migration involved in gastrulation

MGI:MGI:4849883
PMID:21069829[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0043547

positive regulation of GTPase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001093990

P

From MGI

GO:0070586

cell-cell adhesion involved in gastrulation

MGI:MGI:4849883
PMID:21069829[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI

GO:0071711

basement membrane organization

MGI:MGI:4849883
PMID:21069829[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3608888

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Tõnissoo T et al. (2006) Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety. Behav Brain Res 167: 42-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Tõnissoo T et al. (2010) Nucleotide exchange factor RIC-8 is indispensable in mammalian early development. Dev Dyn 239: 3404-15 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Wang SC et al. (2007) Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor. Biochem J 406: 383-8 PubMed GONUTS page
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