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MGI:Rhob
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Rhob ( synonyms: Arhb ) | |
| Protein Name(s) | ras homolog gene family, member B, | |
| External Links | ||
| MGI | MGI:107949 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0001525 |
angiogenesis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0037 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:77862 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:84225 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005525 |
GTP binding |
MGI:MGI:3687438 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:84225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:84225 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2679407 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005768 |
endosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0967 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:3039970 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006915 |
apoptotic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0053 |
P |
From MGI |
||
| GO:0006927 |
transformed cell apoptotic process |
MGI:MGI:3688063 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:2150450 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0008333 |
endosome to lysosome transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010008 |
endosome membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0015031 |
protein transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0653 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0019003 |
GDP binding |
MGI:MGI:84225 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0032154 |
cleavage furrow |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0033205 |
cell cycle cytokinesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045766 |
positive regulation of angiogenesis |
MGI:MGI:2679407 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045786 |
negative regulation of cell cycle |
MGI:MGI:2150450 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070301 |
cellular response to hydrogen peroxide |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071479 |
cellular response to ionizing radiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Madaule P et al. (1995) A novel partner for the GTP-bound forms of rho and rac. FEBS Lett 377: 243-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Zalcman G et al. (1996) RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. J Biol Chem 271: 30366-74 PubMed GONUTS page
- ↑ Adamson P et al. (1992) Post-translational modifications of p21rho proteins. J Biol Chem 267: 20033-8 PubMed GONUTS page
- ↑ 4.0 4.1 Adini I et al. (2003) RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev 17: 2721-32 PubMed GONUTS page
- ↑ Yonemura S et al. (2004) Rho localization in cells and tissues. Exp Cell Res 295: 300-14 PubMed GONUTS page
- ↑ Liu Ax et al. (2001) RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage. Proc Natl Acad Sci U S A 98: 6192-7 PubMed GONUTS page
- ↑ 7.0 7.1 Liu AX et al. (2001) RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells. Mol Cell Biol 21: 6906-12 PubMed GONUTS page
