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MGI:Rgnef

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rgnef ( synonyms: D13Bwg1089e, p190RhoGEF, Rho specific exchange factor, RhoGEF, RIP2 )
Protein Name(s) Rho-guanine nucleotide exchange factor,
External Links
MGI MGI:1346016

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003723

RNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From MGI

GO:0005085

guanyl-nucleotide exchange factor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

F

From MGI

GO:0005089

Rho guanyl-nucleotide exchange factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

F

From MGI

GO:0005515

protein binding

MGI:MGI:3619625
PMID:16236762[1]

IPI: Inferred from Physical Interaction

UniProtKB:P08551

F

From MGI

GO:0005543

phospholipid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N1W1

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0015630

microtubule cytoskeleton

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8N1W1

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0021955

central nervous system neuron axonogenesis

MGI:MGI:3056242
PMID:15378065[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0035023

regulation of Rho protein signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From MGI

GO:0035556

intracellular signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR002219

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

P

From MGI

GO:0050790

regulation of catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000219

P

From MGI

GO:0060052

neurofilament cytoskeleton organization

MGI:MGI:3619625
PMID:16236762[1]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lin H et al. (2005) RNA-binding protein is involved in aggregation of light neurofilament protein and is implicated in the pathogenesis of motor neuron degeneration. Hum Mol Genet 14: 3643-59 PubMed GONUTS page
  2. Rico B et al. (2004) Control of axonal branching and synapse formation by focal adhesion kinase. Nat Neurosci 7: 1059-69 PubMed GONUTS page
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