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MGI:Rfx4

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rfx4
Protein Name(s) regulatory factor X, 4 (influences HLA class II expression),
External Links
MGI MGI:1918387

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From MGI

GO:0003677

DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003150

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:3701709
PMID:16893423[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3790945
PMID:18218630[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9WV81
UniProtKB:A2A870
UniProtKB:Q3TI61
UniProtKB:Q3UNV7

F

From MGI

GO:0005634

nucleus

MGI:MGI:3701709
PMID:16893423[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3790945
PMID:18218630[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003150

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:3701709
PMID:16893423[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:3790945
PMID:18218630[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0021516

dorsal spinal cord development

MGI:MGI:2669568
PMID:12925582[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0021696

cerebellar cortex morphogenesis

MGI:MGI:2669568
PMID:12925582[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030900

forebrain development

MGI:MGI:2669568
PMID:12925582[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030901

midbrain development

MGI:MGI:2669568
PMID:12925582[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3701709
PMID:16893423[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3790945
PMID:18218630[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Zhang D et al. (2006) Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development. J Neurochem 98: 860-75 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Zhang D et al. (2008) G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator. J Biol Chem 283: 8580-90 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Blackshear PJ et al. (2003) Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development 130: 4539-52 PubMed GONUTS page
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