MGI:Rela

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0001889	liver development	MGI:MGI:76008 PMID:7603567^[1]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0001942	hair follicle development	MGI:MGI:3618958 PMID:16481354^[2]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0003677	DNA binding	MGI:MGI:3041925 PMID:14961764^[3]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3575325 PMID:15790681^[4]	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3576806 PMID:15845452^[5]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3578695 PMID:15684432^[6]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3589852 PMID:15944286^[7]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3607973 PMID:16260493^[8]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3608264 PMID:16207754^[9]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3805145 PMID:18505784^[10]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0003682	chromatin binding	MGI:MGI:4355652 PMID:19619491^[11]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003682	chromatin binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0003682	chromatin binding	MGI:MGI:4946475 PMID:21131967^[12]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003700	sequence-specific DNA binding transcription factor activity	MGI:MGI:2679145 PMID:14568984^[13]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003700	sequence-specific DNA binding transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	MGI:MGI:3687432 PMID:8289784^[14]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3530389 PMID:15661756^[15]	IPI: Inferred from Physical Interaction	UniProtKB:Q5I1X5	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3687926 PMID:11931769^[16]	IPI: Inferred from Physical Interaction	UniProtKB:O09106	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3688344 PMID:15102471^[17]	IPI: Inferred from Physical Interaction	UniProtKB:Q60778 UniProtKB:Q9Z1E3	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3763312 PMID:9556555^[18]	IPI: Inferred from Physical Interaction	UniProtKB:P25799	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3814108 PMID:18710934^[19]	IPI: Inferred from Physical Interaction	UniProtKB:O35516	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3850810 PMID:19345186^[20]	IPI: Inferred from Physical Interaction	UniProtKB:Q06219	F	From MGI
	GO:0005515	protein binding	MGI:MGI:4946475 PMID:21131967^[12]	IPI: Inferred from Physical Interaction	UniProtKB:Q8TBK2	F	From MGI
	GO:0005515	protein binding	MGI:MGI:5086034 PMID:21725320^[21]	IPI: Inferred from Physical Interaction	UniProtKB:Q62227	F	From MGI
	GO:0005515	protein binding	MGI:MGI:5284781 PMID:17254973^[22]	IPI: Inferred from Physical Interaction	UniProtKB:P25799:PRO_0000030312 UniProtKB:Q9Z1E3	F	From MGI
	GO:0005515	protein binding	MGI:MGI:5284810 PMID:12686541^[23]	IPI: Inferred from Physical Interaction	UniProtKB:Q60778	F	From MGI
	GO:0005515	protein binding	MGI:MGI:5304595 PMID:22244329^[24]	IPI: Inferred from Physical Interaction	UniProtKB:P23396	F	From MGI
	GO:0005634	nucleus	MGI:MGI:2154675 PMID:11567019^[25]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:2177878 PMID:11931770^[26]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3041925 PMID:14961764^[3]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3050756 PMID:15220916^[27]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3530402 PMID:15661922^[28]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3575325 PMID:15790681^[4]	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	C	From MGI
	GO:0005634	nucleus	MGI:MGI:3581936 PMID:15817708^[29]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3624478 PMID:16643855^[30]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3769059 PMID:16249387^[31]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3844151 PMID:19404405^[32]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:4353631 PMID:12527755^[33]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	C	From MGI
	GO:0005634	nucleus	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	C	From MGI
	GO:0005634	nucleus	MGI:MGI:4946475 PMID:21131967^[12]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:5291872 PMID:21874024^[34]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:5304595 PMID:22244329^[24]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005667	transcription factor complex	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:2154675 PMID:11567019^[25]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:3041925 PMID:14961764^[3]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:3575325 PMID:15790681^[4]	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:3624478 PMID:16643855^[30]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:3769059 PMID:16249387^[31]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:3844151 PMID:19404405^[32]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:4353631 PMID:12527755^[33]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:4946475 PMID:21131967^[12]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005829	cytosol	MGI:MGI:2177878 PMID:11931770^[26]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005829	cytosol	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	C	From MGI
	GO:0006351	transcription, DNA-dependent	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0804	P	From MGI
	GO:0006355	regulation of transcription, DNA-dependent	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0805	P	From MGI
	GO:0006355	regulation of transcription, DNA-dependent	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR000451 InterPro:IPR008967 InterPro:IPR011539	P	From MGI
	GO:0006357	regulation of transcription from RNA polymerase II promoter	MGI:MGI:3687432 PMID:8289784^[14]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0006916	anti-apoptosis	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0006916	anti-apoptosis	MGI:MGI:5304595 PMID:22244329^[24]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0006952	defense response	MGI:MGI:1860430 PMID:9120401^[35]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1860444	P	From MGI
	GO:0006954	inflammatory response	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0008134	transcription factor binding	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	F	From MGI
	GO:0008134	transcription factor binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0008284	positive regulation of cell proliferation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	P	From MGI
	GO:0009617	response to bacterium	MGI:MGI:3530402 PMID:15661922^[28]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0009887	organ morphogenesis	MGI:MGI:1860430 PMID:9120401^[35]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1860444	P	From MGI
	GO:0010033	response to organic substance	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0010224	response to UV-B	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0014040	positive regulation of Schwann cell differentiation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	P	From MGI
	GO:0019221	cytokine-mediated signaling pathway	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0019899	enzyme binding	MGI:MGI:5304595 PMID:22244329^[24]	IPI: Inferred from Physical Interaction	UniProtKB:Q8VCN5	F	From MGI
	GO:0019901	protein kinase binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0019901	protein kinase binding	MGI:MGI:4946475 PMID:21131967^[12]	IPI: Inferred from Physical Interaction	UniProtKB:Q02956	F	From MGI
	GO:0031625	ubiquitin protein ligase binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0032332	positive regulation of chondrocyte differentiation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	P	From MGI
	GO:0032403	protein complex binding	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	F	From MGI
	GO:0032495	response to muramyl dipeptide	MGI:MGI:4353631 PMID:12527755^[33]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0033613	activating transcription factor binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0042177	negative regulation of protein catabolic process	MGI:MGI:3581324 PMID:15923614^[36]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0042301	phosphate ion binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0042802	identical protein binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0043066	negative regulation of apoptotic process	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	MGI:MGI:5304595 PMID:22244329^[24]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0043234	protein complex	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	C	From MGI
	GO:0043565	sequence-specific DNA binding	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	F	From MGI
	GO:0044212	transcription regulatory region DNA binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0045084	positive regulation of interleukin-12 biosynthetic process	MGI:MGI:2679145 PMID:14568984^[13]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045892	negative regulation of transcription, DNA-dependent	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:1860430 PMID:9120401^[35]	TAS: Traceable Author Statement		P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:2679145 PMID:14568984^[13]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:3805145 PMID:18505784^[10]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:4946475 PMID:21131967^[12]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0046627	negative regulation of insulin receptor signaling pathway	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88619	P	From MGI
	GO:0047485	protein N-terminus binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0050727	regulation of inflammatory response	MGI:MGI:4946475 PMID:21131967^[12]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0051059	NF-kappaB binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0051092	positive regulation of NF-kappaB transcription factor activity	MGI:MGI:3575325 PMID:15790681^[4]	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0051092	positive regulation of NF-kappaB transcription factor activity	MGI:MGI:5304595 PMID:22244329^[24]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	MGI:MGI:2154458	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0070491	repressing transcription factor binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	F	From MGI
	GO:0070555	response to interleukin-1	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0071159	NF-kappaB complex	MGI:MGI:5304595 PMID:22244329^[24]	TAS: Traceable Author Statement		C	From MGI
	GO:0071347	cellular response to interleukin-1	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0071356	cellular response to tumor necrosis factor	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q04206	P	From MGI
	GO:0071532	ankyrin repeat binding	MGI:MGI:4946475 PMID:21131967^[12]	IPI: Inferred from Physical Interaction	UniProtKB:Q5DW34	F	From MGI
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Beg AA et al. (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 376: 167-70 PubMed GONUTS page
↑ Schmidt-Ullrich R et al. (2006) NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development 133: 1045-57 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Liu L et al. (2004) Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling. Biochem J 380: 31-41 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Bettelli E et al. (2005) Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 102: 5138-43 PubMed GONUTS page
↑ Rupec RA et al. (2005) Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity 22: 479-91 PubMed GONUTS page
↑ Makowski L et al. (2005) The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. J Biol Chem 280: 12888-95 PubMed GONUTS page
↑ Ossendorp F et al. (2005) Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells. J Immunol 174: 7815-22 PubMed GONUTS page
↑ Shim JH et al. (2005) TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev 19: 2668-81 PubMed GONUTS page
↑ Sawada A et al. (2005) Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor. Development 132: 4719-29 PubMed GONUTS page
↑ ^10.0 ^10.1 Mitola S et al. (2008) Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm. Blood 112: 1154-7 PubMed GONUTS page
↑ Zhang Y et al. (2009) Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell 17: 49-61 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 ^12.3 ^12.4 ^12.5 ^12.6 ^12.7 Levy D et al. (2011) Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol 12: 29-36 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 Liu J et al. (2003) Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-gamma-primed IL-12 production by IFN regulatory factor 1. J Exp Med 198: 1265-76 PubMed GONUTS page
↑ ^14.0 ^14.1 La Rosa FA et al. (1994) Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors. Mol Cell Biol 14: 1039-44 PubMed GONUTS page
↑ Herron BJ et al. (2005) A mutation in NFkB interacting protein 1 results in cardiomyopathy and abnormal skin development in wa3 mice. Hum Mol Genet 14: 667-77 PubMed GONUTS page
↑ Zhong H et al. (2002) The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 9: 625-36 PubMed GONUTS page
↑ Papin J & Subramaniam S (2004) Bioinformatics and cellular signaling. Curr Opin Biotechnol 15: 78-81 PubMed GONUTS page
↑ Na SY et al. (1998) Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations. J Biol Chem 273: 10831-4 PubMed GONUTS page
↑ Fukushima H et al. (2008) The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis. Mol Cell Biol 28: 6402-12 PubMed GONUTS page
↑ Saijo K et al. (2009) A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137: 47-59 PubMed GONUTS page
↑ Yuk JM et al. (2011) The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors. Nat Immunol 12: 742-51 PubMed GONUTS page
↑ Basak S et al. (2007) A fourth IkappaB protein within the NF-kappaB signaling module. Cell 128: 369-81 PubMed GONUTS page
↑ Malek S et al. (2003) X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex. J Biol Chem 278: 23094-100 PubMed GONUTS page
↑ ^24.0 ^24.1 ^24.2 ^24.3 ^24.4 ^24.5 ^24.6 Sen N et al. (2012) Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions. Mol Cell 45: 13-24 PubMed GONUTS page
↑ ^25.0 ^25.1 Kim RH et al. (2001) SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. J Biol Chem 276: 46297-304 PubMed GONUTS page
↑ ^26.0 ^26.1 Fiorini E et al. (2002) Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor. Mol Cell 9: 637-48 PubMed GONUTS page
↑ Watanabe T et al. (2004) NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5: 800-8 PubMed GONUTS page
↑ ^28.0 ^28.1 O'Connell RM et al. (2005) Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1. J Immunol 174: 1602-7 PubMed GONUTS page
↑ Wilmanski J et al. (2005) Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages. J Leukoc Biol 78: 85-94 PubMed GONUTS page
↑ ^30.0 ^30.1 Minoda Y et al. (2006) A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling. Biochem Biophys Res Commun 344: 1023-30 PubMed GONUTS page
↑ ^31.0 ^31.1 Ahn E et al. (2006) LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation. Blood 107: 1521-7 PubMed GONUTS page
↑ ^32.0 ^32.1 Esteban V et al. (2009) Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation. PLoS One 4: e5406 PubMed GONUTS page
↑ ^33.0 ^33.1 ^33.2 Girardin SE et al. (2003) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278: 8869-72 PubMed GONUTS page
↑ Chang M et al. (2011) The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nat Immunol 12: 1002-9 PubMed GONUTS page
↑ ^35.0 ^35.1 ^35.2 Doi TS et al. (1997) NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J Exp Med 185: 953-61 PubMed GONUTS page
↑ Hertlein E et al. (2005) RelA/p65 regulation of IkappaBbeta. Mol Cell Biol 25: 4956-68 PubMed GONUTS page

[PMID:7603567-0] Beg AA et al. (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 376: 167-70 PubMed GONUTS page

[PMID:16481354-1] Schmidt-Ullrich R et al. (2006) NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development 133: 1045-57 PubMed GONUTS page

[PMID:14961764-2] 3.0 ^3.1 ^3.2 Liu L et al. (2004) Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling. Biochem J 380: 31-41 PubMed GONUTS page

[PMID:15790681-3] 4.0 ^4.1 ^4.2 ^4.3 Bettelli E et al. (2005) Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A 102: 5138-43 PubMed GONUTS page

[PMID:15845452-4] Rupec RA et al. (2005) Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity 22: 479-91 PubMed GONUTS page

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Species (Taxon ID)	Mus musculus (house mouse) (taxon:10090)
Gene Name(s)	Rela ( synonyms: p65, p65 NF kappaB )
Protein Name(s)	v-rel reticuloendotheliosis viral oncogene homolog A (avian),
External Links
MGI	MGI:103290

MGI:Rela

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