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MGI:Rdx

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rdx
Protein Name(s) radixin,
External Links
MGI MGI:97887

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001726

ruffle

MGI:MGI:1202233
PMID:9563848[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0003779

actin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0009

F

From MGI

GO:0005515

protein binding

MGI:MGI:2181857
PMID:12068294[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q8VI47
UniProtKB:P35330
UniProtKB:P15702

F

From MGI

GO:0005730

nucleolus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:A7YIJ8

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011174
InterPro:IPR011259
InterPro:IPR000798
InterPro:IPR008954

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:A7YIJ8

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

From MGI

GO:0005856

cytoskeleton

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000299

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001005889

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:A7YIJ8

C

From MGI

GO:0005902

microvillus

MGI:MGI:2181857
PMID:12068294[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005902

microvillus

MGI:MGI:3039970
PMID:15093731[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005902

microvillus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001005889

C

From MGI

GO:0008092

cytoskeletal protein binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011174
InterPro:IPR011259
InterPro:IPR000798
InterPro:IPR008954

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0019898

extrinsic to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011174
InterPro:IPR011259
InterPro:IPR000798
InterPro:IPR008954

C

From MGI

GO:0030027

lamellipodium

MGI:MGI:1202233
PMID:9563848[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030033

microvillus assembly

MGI:MGI:2181857
PMID:12068294[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2671151

P

From MGI

GO:0030175

filopodium

MGI:MGI:1202233
PMID:9563848[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0032420

stereocilium

MGI:MGI:3663248
PMID:17021174[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0045176

apical protein localization

MGI:MGI:2181857
PMID:12068294[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2671151

P

From MGI

GO:0045176

apical protein localization

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001005889

P

From MGI

GO:0045177

apical part of cell

MGI:MGI:1330678
PMID:9890997[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0051693

actin filament capping

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0117

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Shaw RJ et al. (1998) Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin. Cell Growth Differ 9: 287-96 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Kikuchi S et al. (2002) Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet 31: 320-5 PubMed GONUTS page
  3. Yonemura S et al. (2004) Rho localization in cells and tissues. Exp Cell Res 295: 300-14 PubMed GONUTS page
  4. Gagnon LH et al. (2006) The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. J Neurosci 26: 10188-98 PubMed GONUTS page
  5. Doi Y et al. (1999) Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout. J Biol Chem 274: 2315-21 PubMed GONUTS page
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