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MGI:Rbx1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Rbx1 ( synonyms: ROC1 ) | |
| Protein Name(s) | ring-box 1, | |
| External Links | ||
| MGI | MGI:1891829 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000151 |
ubiquitin ligase complex |
MGI:MGI:3687685 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:3687685 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3042352 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3513692 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3653956 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005680 |
anaphase-promoting complex |
MGI:MGI:3687685 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0963 |
C |
From MGI |
||
| GO:0005829 |
cytosol |
MGI:MGI:4821082 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006511 |
ubiquitin-dependent protein catabolic process |
MGI:MGI:3687685 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006513 |
protein monoubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006513 |
protein monoubiquitination |
MGI:MGI:5009099 |
IGI: Inferred from Genetic Interaction |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0227 |
P |
From MGI |
||
| GO:0008190 |
eukaryotic initiation factor 4E binding |
MGI:MGI:3687688 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:1890005 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:4821082 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016567 |
protein ubiquitination |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016874 |
ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From MGI |
||
| GO:0019005 |
SCF ubiquitin ligase complex |
MGI:MGI:1890005 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0019005 |
SCF ubiquitin ligase complex |
MGI:MGI:3653956 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0019005 |
SCF ubiquitin ligase complex |
MGI:MGI:4821082 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0019005 |
SCF ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0019788 |
NEDD8 ligase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030163 |
protein catabolic process |
MGI:MGI:3513692 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030891 |
VCB complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001029307 |
C |
From MGI |
||
| GO:0031146 |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
MGI:MGI:4821082 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0031146 |
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031462 |
Cul2-RING ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031463 |
Cul3-RING ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031464 |
Cul4A-RING ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031465 |
Cul4B-RING ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031466 |
Cul5-RING ubiquitin ligase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001029307 |
F |
From MGI |
||
| GO:0043161 |
proteasomal ubiquitin-dependent protein catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045116 |
protein neddylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ohta T et al. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3: 535-41 PubMed GONUTS page
- ↑ Nastasi T et al. (2004) Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis. Dev Cell 6: 269-82 PubMed GONUTS page
- ↑ 3.0 3.1 Kamura T et al. (2004) VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. Genes Dev 18: 3055-65 PubMed GONUTS page
- ↑ 4.0 4.1 Tsunematsu R et al. (2006) Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development. Mol Cell Biol 26: 6157-69 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Yoshida Y et al. (2002) E3 ubiquitin ligase that recognizes sugar chains. Nature 418: 438-42 PubMed GONUTS page
- ↑ Chen BB et al. (2011) Calmodulin antagonizes a calcium-activated SCF ubiquitin E3 ligase subunit, FBXL2, to regulate surfactant homeostasis. Mol Cell Biol 31: 1905-20 PubMed GONUTS page
- ↑ Skowyra D et al. (1999) Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1. Science 284: 662-5 PubMed GONUTS page
- ↑ 8.0 8.1 Kamura T et al. (1999) Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284: 657-61 PubMed GONUTS page
