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MGI:Rb1cc1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Rb1cc1 ( synonyms: Cc1, Fip200, LaXp180 ) | |
| Protein Name(s) | RB1-inducible coiled-coil 1, | |
| External Links | ||
| MGI | MGI:1341850 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000045 |
autophagic vacuole assembly |
MGI:MGI:3849242 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0000407 |
pre-autophagosomal structure |
MGI:MGI:3849242 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001889 |
liver development |
MGI:MGI:3689241 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3690329 |
P |
From MGI |
||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:3689241 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3690329 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3849242 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3689241 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104798 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:1928264 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2182913 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1928264 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0006914 |
autophagy |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0072 |
P |
From MGI |
||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007254 |
JNK cascade |
MGI:MGI:3689241 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:104798 |
P |
From MGI |
||
| GO:0007507 |
heart development |
MGI:MGI:3689241 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3690329 |
P |
From MGI |
||
| GO:0010506 |
regulation of autophagy |
MGI:MGI:3796758 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0019901 |
protein kinase binding |
MGI:MGI:3796758 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0034045 |
pre-autophagosomal structure membrane |
MGI:MGI:3796758 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3689241 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3690329 |
P |
From MGI |
||
| GO:0045793 |
positive regulation of cell size |
MGI:MGI:3689241 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3690329 |
P |
From MGI |
||
| GO:0070969 |
ULK1-ATG13-FIP200 complex |
MGI:MGI:3849242 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0070969 |
ULK1-ATG13-FIP200 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ganley IG et al. (2009) ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 284: 12297-305 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gan B et al. (2006) Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol 175: 121-33 PubMed GONUTS page
- ↑ 3.0 3.1 Pfeuffer T et al. (2000) LaXp180, a mammalian ActA-binding protein, identified with the yeast two-hybrid system, co-localizes with intracellular Listeria monocytogenes. Cell Microbiol 2: 101-14 PubMed GONUTS page
- ↑ Chano T et al. (2002) Isolation, characterization and mapping of the mouse and human RB1CC1 genes. Gene 291: 29-34 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Hara T et al. (2008) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol 181: 497-510 PubMed GONUTS page
