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MGI:Rasgrp3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rasgrp3 ( synonyms: LOC240168 )
Protein Name(s) RAS, guanyl releasing protein 3,
External Links
MGI MGI:3028579

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005085

guanyl-nucleotide exchange factor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0344

F

From MGI

GO:0005088

Ras guanyl-nucleotide exchange factor activity

MGI:MGI:3512842
PMID:15545601[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:3512842
PMID:15545601[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3583869
PMID:15894621[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007265

Ras protein signal transduction

MGI:MGI:3512842
PMID:15545601[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0017016

Ras GTPase binding

MGI:MGI:3512842
PMID:15545601[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0017016

Ras GTPase binding

MGI:MGI:3583869
PMID:15894621[2]

IPI: Inferred from Physical Interaction

UniProtKB:P62835

F

From MGI

GO:0019900

kinase binding

MGI:MGI:3583869
PMID:15894621[2]

IPI: Inferred from Physical Interaction

RefSeq:NP_001074675

F

From MGI

GO:0032045

guanyl-nucleotide exchange factor complex

MGI:MGI:3583869
PMID:15894621[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0032854

positive regulation of Rap GTPase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8IV61

P

From MGI

GO:0043087

regulation of GTPase activity

MGI:MGI:3512842
PMID:15545601[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046582

Rap GTPase activator activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8IV61

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:3583869
PMID:15894621[2]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Aiba Y et al. (2004) Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation. Proc Natl Acad Sci U S A 101: 16612-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Regier DS et al. (2005) Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling. Proc Natl Acad Sci U S A 102: 7595-600 PubMed GONUTS page
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