GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Rapsn
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Rapsn ( synonyms: 43kDa acetylcholine receptor-associated protein, Nraps, Raps, rapsyn ) | |
| Protein Name(s) | receptor-associated protein of the synapse, | |
| External Links | ||
| MGI | MGI:99422 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:2388930 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005856 |
cytoskeleton |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:2388930 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007268 |
synaptic transmission |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007271 |
synaptic transmission, cholinergic |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030054 |
cell junction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0031594 |
neuromuscular junction |
MGI:MGI:3703100 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031594 |
neuromuscular junction |
MGI:MGI:84411 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0033130 |
acetylcholine receptor binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0033130 |
acetylcholine receptor binding |
MGI:MGI:3797335 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0035255 |
ionotropic glutamate receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001102054 |
F |
From MGI |
||
| GO:0043525 |
positive regulation of neuron apoptotic process |
MGI:MGI:2137500 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2148091 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0628 |
C |
From MGI |
||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Marchand S et al. (2002) Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J Neurosci 22: 8891-901 PubMed GONUTS page
- ↑ Weatherbee SD et al. (2006) LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development 133: 4993-5000 PubMed GONUTS page
- ↑ Noakes PG et al. (1993) 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol 155: 275-80 PubMed GONUTS page
- ↑ Osman AA et al. (2008) Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear. Mol Cell Neurosci 38: 153-69 PubMed GONUTS page
- ↑ Terrado J et al. (2001) Motoneuron survival is enhanced in the absence of neuromuscular junction formation in embryos. J Neurosci 21: 3144-50 PubMed GONUTS page
