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MGI:Rad9

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rad9
Protein Name(s) RAD9 homolog (S. pombe),
External Links
MGI MGI:1328356

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000075

cell cycle checkpoint

MGI:MGI:1289930
PMID:9766521[1]

IGI: Inferred from Genetic Interaction

P

From MGI

GO:0000077

DNA damage checkpoint

MGI:MGI:1927035
PMID:11058134[2]

ISS: Inferred from Sequence or Structural Similarity

P

From MGI

GO:0000077

DNA damage checkpoint

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

P

From MGI

GO:0004518

nuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From MGI

GO:0004527

exonuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

F

From MGI

GO:0005515

protein binding

MGI:MGI:3584078
PMID:15983387[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q3TQR0
UniProtKB:P10417

F

From MGI

GO:0005634

nucleus

MGI:MGI:3584078
PMID:15983387[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3584078
PMID:15983387[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006281

DNA repair

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From MGI

GO:0006281

DNA repair

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR007268

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

P

From MGI

GO:0008408

3'-5' exonuclease activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

F

From MGI

GO:0008853

exodeoxyribonuclease III activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.1.11.2

F

From MGI

GO:0009314

response to radiation

MGI:MGI:1927035
PMID:11058134[2]

ISS: Inferred from Sequence or Structural Similarity

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

F

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

F

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

F

From MGI

GO:0042826

histone deacetylase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

F

From MGI

GO:0043065

positive regulation of apoptotic process

MGI:MGI:3584078
PMID:15983387[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0071479

cellular response to ionizing radiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.1.11.2

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q99638

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Hang H et al. (1998) Molecular cloning and tissue-specific expression of Mrad9, a murine orthologue of the Schizosaccharomyces pombe rad9+ checkpoint control gene. J Cell Physiol 177: 241-7 PubMed GONUTS page
  2. 2.0 2.1 Hang H et al. (2000) Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control. Nucleic Acids Res 28: 4340-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Ishii H et al. (2005) Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis. Proc Natl Acad Sci U S A 102: 9655-60 PubMed GONUTS page
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