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MGI:Rab7

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rab7
Protein Name(s) RAB7, member RAS oncogene family,
External Links
MGI MGI:105068

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0003924

GTPase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

F

From MGI

GO:0005515

protein binding

MGI:MGI:4821079
PMID:12972561[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9D0C1

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

F

From MGI

GO:0005622

intracellular

MGI:MGI:1930444
PMID:11042173[2]

TAS: Traceable Author Statement

C

From MGI

GO:0005764

lysosome

MGI:MGI:3040541
PMID:15078902[3]

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

C

From MGI

GO:0005768

endosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

From MGI

GO:0005770

late endosome

MGI:MGI:2387806
PMID:11172003[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005770

late endosome

MGI:MGI:3040541
PMID:15078902[3]

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

C

From MGI

GO:0005770

late endosome

MGI:MGI:3527911
PMID:15588329[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005770

late endosome

MGI:MGI:4361100
PMID:19509052[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005770

late endosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

C

From MGI

GO:0005770

late endosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

C

From MGI

GO:0005770

late endosome

MGI:MGI:4868574
PMID:20943658[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:1930444
PMID:11042173[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

C

From MGI

GO:0006184

GTP catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

P

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006886

intracellular protein transport

MGI:MGI:1930444
PMID:11042173[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007174

epidermal growth factor catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

P

From MGI

GO:0007264

small GTPase mediated signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003579

P

From MGI

GO:0008333

endosome to lysosome transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

P

From MGI

GO:0015031

protein transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

From MGI

GO:0015031

protein transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003579

P

From MGI

GO:0019003

GDP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

F

From MGI

GO:0019003

GDP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

F

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

C

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

C

From MGI

GO:0045022

early endosome to late endosome transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P51149

P

From MGI

GO:0045453

bone resorption

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

P

From MGI

GO:0048365

Rac GTPase binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

F

From MGI

GO:0097208

alveolar lamellar body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P09527

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Mizuno K et al. (2003) Rabring7, a novel Rab7 target protein with a RING finger motif. Mol Biol Cell 14: 3741-52 PubMed GONUTS page
  2. 2.0 2.1 2.2 Bell AW et al. (2001) Proteomics characterization of abundant Golgi membrane proteins. J Biol Chem 276: 5152-65 PubMed GONUTS page
  3. 3.0 3.1 Seaman MN (2004) Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J Cell Biol 165: 111-22 PubMed GONUTS page
  4. Cormont M et al. (2001) A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic. Proc Natl Acad Sci U S A 98: 1637-42 PubMed GONUTS page
  5. Fossale E et al. (2004) Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis. BMC Neurosci 5: 57 PubMed GONUTS page
  6. Schaheen B et al. (2009) Derlin-dependent accumulation of integral membrane proteins at cell surfaces. J Cell Sci 122: 2228-39 PubMed GONUTS page
  7. Mayer PR et al. (2010) Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2. J Biol Chem 285: 40387-96 PubMed GONUTS page
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