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MGI:Rab27b

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Rab27b
Protein Name(s) RAB27b, member RAS oncogene family,
External Links
MGI MGI:1931295

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0003924

GTPase activity

MGI:MGI:4412434
PMID:18940604[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:3693417
PMID:16716193[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q99N50

F

From MGI

GO:0005515

protein binding

MGI:MGI:4412434
PMID:18940604[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q91V27

F

From MGI

GO:0005525

GTP binding

MGI:MGI:4412434
PMID:18940604[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003579

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:3040020
PMID:14724135[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

C

From MGI

GO:0005795

Golgi stack

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

C

From MGI

GO:0006184

GTP catabolic process

MGI:MGI:4412434
PMID:18940604[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007264

small GTPase mediated signal transduction

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003579

P

From MGI

GO:0015031

protein transport

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR003579

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016324

apical plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445911

C

From MGI

GO:0017157

regulation of exocytosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445911

P

From MGI

GO:0019904

protein domain specific binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

F

From MGI

GO:0030140

trans-Golgi network transport vesicle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

C

From MGI

GO:0030667

secretory granule membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445911

C

From MGI

GO:0032585

multivesicular body membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

C

From MGI

GO:0042589

zymogen granule membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445911

C

From MGI

GO:0045921

positive regulation of exocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

P

From MGI

GO:0071985

multivesicular body sorting pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O00194

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Kukimoto-Niino M et al. (2008) Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure 16: 1478-90 PubMed GONUTS page
  2. Saegusa C et al. (2006) Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells. Genes Cells 11: 623-31 PubMed GONUTS page
  3. Kierszenbaum AL et al. (2004) The acroplaxome is the docking site of Golgi-derived myosin Va/Rab27a/b- containing proacrosomal vesicles in wild-type and Hrb mutant mouse spermatids. Biol Reprod 70: 1400-10 PubMed GONUTS page
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