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MGI:Pxmp3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pxmp3 ( synonyms: D3Ertd138e, peroxisome biogenesis factor 2, Pex2, PMP35, Pxmp3, Zellweger syndrome homolog ) | |
| Protein Name(s) | peroxisomal membrane protein 3, | |
| External Links | ||
| MGI | MGI:107486 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001764 |
neuron migration |
MGI:MGI:2662803 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180128 |
P |
From MGI |
||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005777 |
peroxisome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005778 |
peroxisomal membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005779 |
integral to peroxisomal membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006635 |
fatty acid beta-oxidation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006699 |
bile acid biosynthetic process |
MGI:MGI:3027293 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180128 |
P |
From MGI |
||
| GO:0007031 |
peroxisome organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007399 |
nervous system development |
MGI:MGI:2662803 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180128 |
P |
From MGI |
||
| GO:0008270 |
zinc ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016558 |
protein import into peroxisome matrix |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016593 |
Cdc73/Paf1 complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031648 |
protein destabilization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:3027293 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180128 |
P |
From MGI |
||
| GO:0045540 |
regulation of cholesterol biosynthetic process |
MGI:MGI:3027293 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2180128 |
P |
From MGI |
||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048147 |
negative regulation of fibroblast proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050680 |
negative regulation of epithelial cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Faust PL (2003) Abnormal cerebellar histogenesis in PEX2 Zellweger mice reflects multiple neuronal defects induced by peroxisome deficiency. J Comp Neurol 461: 394-413 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kovacs WJ et al. (2004) Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model. Mol Cell Biol 24: 1-13 PubMed GONUTS page
