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MGI:Pttg1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pttg1 ( synonyms: PTTG, securin )
Protein Name(s) pituitary tumor-transforming gene 1,
External Links
MGI MGI:1353578

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001558

regulation of cell growth

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97613

P

From MGI

GO:0004869

cysteine-type endopeptidase inhibitor activity

MGI:MGI:2678956
PMID:14561405[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O95997

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O95997

C

From MGI

GO:0006259

DNA metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006940

P

From MGI

GO:0006281

DNA repair

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0007059

chromosome segregation

MGI:MGI:3622516
PMID:16533945[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:2146156

P

From MGI

GO:0007067

mitosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0498

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97613

P

From MGI

GO:0009987

cellular process

MGI:MGI:1355002
PMID:10727870[3]

ISA: Inferred from Sequence Alignment

EMBL:AF062649

P

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0729

F

From MGI

GO:0031072

heat shock protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97613

F

From MGI

GO:0043022

ribosome binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97613

F

From MGI

GO:0045143

homologous chromosome segregation

MGI:MGI:2678956
PMID:14561405[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051276

chromosome organization

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006940

P

From MGI

GO:0051301

cell division

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Terret ME et al. (2003) The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity. Curr Biol 13: 1797-802 PubMed GONUTS page
  2. Wirth KG et al. (2006) Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression. J Cell Biol 172: 847-60 PubMed GONUTS page
  3. Tarabykin V et al. (2000) Expression of PTTG and prc1 genes during telencephalic neurogenesis. Mech Dev 92: 301-4 PubMed GONUTS page
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