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MGI:Ptrf

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ptrf ( synonyms: Cavin )
Protein Name(s) polymerase I and transcript release factor,
External Links
MGI MGI:1277968

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003723

RNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From MGI

GO:0005634

nucleus

MGI:MGI:3710718
PMID:15242332[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q6NZI2

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:3710715
PMID:17026959[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q6NZI2

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3710718
PMID:15242332[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q6NZI2

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0256

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0005901

caveola

MGI:MGI:3710715
PMID:17026959[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q6NZI2

C

From MGI

GO:0005901

caveola

MGI:MGI:3773762
PMID:18191225[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005901

caveola

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P85125

C

From MGI

GO:0005901

caveola

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006353

transcription termination, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0806

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006361

transcription initiation from RNA polymerase I promoter

MGI:MGI:3711373
PMID:11139612[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006361

transcription initiation from RNA polymerase I promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

P

From MGI

GO:0006363

termination of RNA polymerase I transcription

MGI:MGI:1266983
PMID:9582279[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006363

termination of RNA polymerase I transcription

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0019843

rRNA binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0699

F

From MGI

GO:0042134

rRNA primary transcript binding

MGI:MGI:1266983
PMID:9582279[5]

IDA: Inferred from Direct Assay

F

From MGI

GO:0042134

rRNA primary transcript binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q6NZI2

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Aboulaich N et al. (2004) Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes. Biochem J 383: 237-48 PubMed GONUTS page
  2. 2.0 2.1 Aboulaich N et al. (2006) Association and insulin regulated translocation of hormone-sensitive lipase with PTRF. Biochem Biophys Res Commun 350: 657-61 PubMed GONUTS page
  3. Hill MM et al. (2008) PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. Cell 132: 113-24 PubMed GONUTS page
  4. Jansa P et al. (2001) The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I. Nucleic Acids Res 29: 423-9 PubMed GONUTS page
  5. 5.0 5.1 Jansa P et al. (1998) Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes. EMBO J 17: 2855-64 PubMed GONUTS page
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