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MGI:Ptpn1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ptpn1 ( synonyms: PTP-1B, PTP1B )
Protein Name(s) protein tyrosine phosphatase, non-receptor type 1,
External Links
MGI MGI:97805

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004721

phosphoprotein phosphatase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0904

F

From MGI

GO:0004725

protein tyrosine phosphatase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

F

From MGI

GO:0004725

protein tyrosine phosphatase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005158

insulin receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

F

From MGI

GO:0005626

insoluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

C

From MGI

GO:0005769

early endosome

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:B4DSN5

C

From MGI

GO:0005829

cytosol

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

C

From MGI

GO:0006470

protein dephosphorylation

MGI:MGI:3528540
PMID:15632081[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0006470

protein dephosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

P

From MGI

GO:0008270

zinc ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

F

From MGI

GO:0008286

insulin receptor signaling pathway

MGI:MGI:3528540
PMID:15632081[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0009966

regulation of signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016311

dephosphorylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000387
InterPro:IPR016130

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0016791

phosphatase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000387
InterPro:IPR016130

F

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

F

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

F

From MGI

GO:0030100

regulation of endocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

P

From MGI

GO:0030968

endoplasmic reticulum unfolded protein response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

P

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

C

From MGI

GO:0031532

actin cytoskeleton reorganization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

P

From MGI

GO:0035335

peptidyl-tyrosine dephosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

P

From MGI

GO:0035335

peptidyl-tyrosine dephosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

P

From MGI

GO:0046626

regulation of insulin receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P20417

P

From MGI

GO:0046875

ephrin receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P18031

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Galic S et al. (2005) Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP. Mol Cell Biol 25: 819-29 PubMed GONUTS page
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