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MGI:Ptk7

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ptk7 ( synonyms: chz, mPTK7/CCK4 )
Protein Name(s) PTK7 protein tyrosine kinase 7,
External Links
MGI MGI:1918711

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001736

establishment of planar polarity

MGI:MGI:4830023
PMID:20704721[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3640803

P

From MGI

GO:0001843

neural tube closure

MGI:MGI:3046397
PMID:15229603[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:2135272

P

From MGI

GO:0001843

neural tube closure

MGI:MGI:3046397
PMID:15229603[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3046905

P

From MGI

GO:0001843

neural tube closure

MGI:MGI:4830023
PMID:20704721[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3640803

P

From MGI

GO:0003401

axis elongation

MGI:MGI:4830023
PMID:20704721[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3640803

P

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245

F

From MGI

GO:0004713

protein tyrosine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008266
InterPro:IPR020635

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0005624

membrane fraction

MGI:MGI:4830023
PMID:20704721[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005911

cell-cell junction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13308

C

From MGI

GO:0007155

cell adhesion

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13308

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

From MGI

GO:0016477

cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13308

P

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0031532

actin cytoskeleton reorganization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13308

P

From MGI

GO:0042060

wound healing

MGI:MGI:4819429
PMID:20643356[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:2655333
MGI:MGI:2145950
MGI:MGI:1100883
MGI:MGI:2135272

P

From MGI

GO:0045198

establishment of epithelial cell apical/basal polarity

MGI:MGI:3046397
PMID:15229603[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3046905

P

From MGI

GO:0060026

convergent extension

MGI:MGI:4830023
PMID:20704721[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3640803

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13308

P

From MGI

GO:0060484

lung-associated mesenchyme development

MGI:MGI:4830023
PMID:20704721[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3640803

P

From MGI

GO:0071300

cellular response to retinoic acid

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13308

P

From MGI

GO:0090103

cochlea morphogenesis

MGI:MGI:4830023
PMID:20704721[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3640803

P

From MGI

GO:0090179

planar cell polarity pathway involved in neural tube closure

MGI:MGI:4830023
PMID:20704721[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1100883
MGI:MGI:2135272

P

From MGI

NOT

GO:0004714

transmembrane receptor protein tyrosine kinase activity

MGI:MGI:3037538
PMID:15019986[4]

IDA: Inferred from Direct Assay

F

From MGI

NOT

GO:0005524

ATP binding

MGI:MGI:3037538
PMID:15019986[4]

IC: Inferred by Curator

GO:0016301

F

From MGI

NOT

GO:0006468

protein phosphorylation

MGI:MGI:3037538
PMID:15019986[4]

IDA: Inferred from Direct Assay

P

From MGI

NOT

GO:0016301

kinase activity

MGI:MGI:3037538
PMID:15019986[4]

IDA: Inferred from Direct Assay

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Paudyal A et al. (2010) The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol 10: 87 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lu X et al. (2004) PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature 430: 93-8 PubMed GONUTS page
  3. Caddy J et al. (2010) Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell 19: 138-47 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Jung JW et al. (2004) Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase. Gene 328: 75-84 PubMed GONUTS page
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