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MGI:Pthr1
From GONUTS
Mus musculus (house mouse)
GO:0001501_!_skeletal_system_development (P) IMP with/from MGI:MGI:2154519 [2]
GO:0001503_!_ossification (P) IMP with/from MGI:MGI:3628795 [3]
GO:0002062_!_chondrocyte_differentiation (P) IGI with/from MGI:MGI:99829 [4]
GO:0002062_!_chondrocyte_differentiation (P) IMP with/from MGI:MGI:2154519 [5]
GO:0002076_!_osteoblast_development (P) IMP with/from MGI:MGI:2154519 [5]
GO:0004871_!_signal_transducer_activity (F) IEA with/from SP_KW:KW-0807 [6]
GO:0004872_!_receptor_activity (F) IEA with/from SP_KW:KW-0675 [6]
GO:0004930_!_G-protein_coupled_receptor_activity (F) IEA with/from SP_KW:KW-0297 [6]
GO:0004930_!_G-protein_coupled_receptor_activity (F) IEA with/from InterPro:IPR001879,InterPro:IPR000832 [7]
GO:0004991_!_parathyroid_hormone_receptor_activity (F) TAS [1]
GO:0004991_!_parathyroid_hormone_receptor_activity (F) IMP with/from MGI:MGI:2154519 [5]
GO:0005622_!_intracellular (C) IDA [8]
GO:0005886_!_plasma_membrane (C) IEA with/from SP_KW:KW-1003 [6]
GO:0006874_!_cellular_calcium_ion_homeostasis (P) IMP with/from MGI:MGI:2154519 [5]
GO:0007165_!_signal_transduction (P) IEA with/from SP_KW:KW-0807 [6]
GO:0007186_!_G-protein_coupled_receptor_protein_signaling_pathway (P) IEA with/from SP_KW:KW-0297 [6]
GO:0007189_!_G-protein_signaling,_adenylate_cyclase_activating_pathway (P) IMP with/from MGI:MGI:2154519 [5]
GO:0007200_!_G-protein_signaling,_coupled_to_IP3_second_messenger_(phospholipase_C_activating) (P) IMP with/from MGI:MGI:3628795 [3]
GO:0008284_!_positive_regulation_of_cell_proliferation (P) IGI with/from MGI:MGI:99829 [4]
GO:0008285_!_negative_regulation_of_cell_proliferation (P) IMP with/from MGI:MGI:3628795 [3]
GO:0016020_!_membrane (C) IEA with/from SP_KW:KW-0472 [6]
GO:0016020_!_membrane (C) IEA with/from InterPro:IPR001879,InterPro:IPR002170,InterPro:IPR000832 [7]
GO:0016021_!_integral_to_membrane (C) IEA with/from SP_KW:KW-0812 [6]
GO:0030282_!_bone_mineralization (P) IMP with/from MGI:MGI:2154519 [1]
GO:0030282_!_bone_mineralization (P) IMP with/from MGI:MGI:2154519 [5]
GO:0045453_!_bone_resorption (P) IMP with/from MGI:MGI:2154519 [5]
GO:0048469_!_cell_maturation (P) IMP with/from MGI:MGI:3628795 [3]
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Pthr1:parathyroid hormone receptor 1
Synonyms:PPR, PTH-related peptide receptor, PTH/PTHrP receptor, PTH1R
Pthr1 on MGI
GO terms
GO:0001501_!_skeletal_system_development (P) IMP with/from MGI:MGI:2154519 [1]GO:0001501_!_skeletal_system_development (P) IMP with/from MGI:MGI:2154519 [2]
GO:0001503_!_ossification (P) IMP with/from MGI:MGI:3628795 [3]
GO:0002062_!_chondrocyte_differentiation (P) IGI with/from MGI:MGI:99829 [4]
GO:0002062_!_chondrocyte_differentiation (P) IMP with/from MGI:MGI:2154519 [5]
GO:0002076_!_osteoblast_development (P) IMP with/from MGI:MGI:2154519 [5]
GO:0004871_!_signal_transducer_activity (F) IEA with/from SP_KW:KW-0807 [6]
GO:0004872_!_receptor_activity (F) IEA with/from SP_KW:KW-0675 [6]
GO:0004930_!_G-protein_coupled_receptor_activity (F) IEA with/from SP_KW:KW-0297 [6]
GO:0004930_!_G-protein_coupled_receptor_activity (F) IEA with/from InterPro:IPR001879,InterPro:IPR000832 [7]
GO:0004991_!_parathyroid_hormone_receptor_activity (F) TAS [1]
GO:0004991_!_parathyroid_hormone_receptor_activity (F) IMP with/from MGI:MGI:2154519 [5]
GO:0005622_!_intracellular (C) IDA [8]
GO:0005886_!_plasma_membrane (C) IEA with/from SP_KW:KW-1003 [6]
GO:0006874_!_cellular_calcium_ion_homeostasis (P) IMP with/from MGI:MGI:2154519 [5]
GO:0007165_!_signal_transduction (P) IEA with/from SP_KW:KW-0807 [6]
GO:0007186_!_G-protein_coupled_receptor_protein_signaling_pathway (P) IEA with/from SP_KW:KW-0297 [6]
GO:0007189_!_G-protein_signaling,_adenylate_cyclase_activating_pathway (P) IMP with/from MGI:MGI:2154519 [5]
GO:0007200_!_G-protein_signaling,_coupled_to_IP3_second_messenger_(phospholipase_C_activating) (P) IMP with/from MGI:MGI:3628795 [3]
GO:0008284_!_positive_regulation_of_cell_proliferation (P) IGI with/from MGI:MGI:99829 [4]
GO:0008285_!_negative_regulation_of_cell_proliferation (P) IMP with/from MGI:MGI:3628795 [3]
GO:0016020_!_membrane (C) IEA with/from SP_KW:KW-0472 [6]
GO:0016020_!_membrane (C) IEA with/from InterPro:IPR001879,InterPro:IPR002170,InterPro:IPR000832 [7]
GO:0016021_!_integral_to_membrane (C) IEA with/from SP_KW:KW-0812 [6]
GO:0030282_!_bone_mineralization (P) IMP with/from MGI:MGI:2154519 [1]
GO:0030282_!_bone_mineralization (P) IMP with/from MGI:MGI:2154519 [5]
GO:0045453_!_bone_resorption (P) IMP with/from MGI:MGI:2154519 [5]
GO:0048469_!_cell_maturation (P) IMP with/from MGI:MGI:3628795 [3]
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Kovacs CS et al. (2001) PTH regulates fetal blood calcium and skeletal mineralization independently of PTHrP. Endocrinology 142: 4983-93 PubMed GONUTS page
- ↑ Lanske B et al. (1996) PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth. Science 273: 663-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Guo J et al. (2002) The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C. Dev Cell 3: 183-94 PubMed GONUTS page
- ↑ 4.0 4.1 Guo J et al. (2006) PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. Dev Biol 292: 116-28 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Lanske B et al. (1998) The parathyroid hormone (PTH)/PTH-related peptide receptor mediates actions of both ligands in murine bone. Endocrinology 139: 5194-204 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 MGI annotation MGI:1354194
- ↑ 7.0 7.1 MGI annotation MGI:2152098
- ↑ Lee K et al. (1996) Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology 137: 5109-18 PubMed GONUTS page
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