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MGI:Pth

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pth
Protein Name(s) parathyroid hormone,
External Links
MGI MGI:97799

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0003705

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

F

From MGI

GO:0005179

hormone activity

MGI:MGI:2153596
PMID:11606467[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005179

hormone activity

MGI:MGI:3525928
PMID:15601870[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005615

extracellular space

MGI:MGI:2153596
PMID:11606467[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005622

intracellular

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

C

From MGI

GO:0005622

intracellular

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

C

From MGI

GO:0006874

cellular calcium ion homeostasis

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

P

From MGI

GO:0006874

cellular calcium ion homeostasis

MGI:MGI:2447255
PMID:12488435[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006874

cellular calcium ion homeostasis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

P

From MGI

GO:0007189

activation of adenylate cyclase activity by G-protein signaling pathway

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

P

From MGI

GO:0007266

Rho protein signal transduction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

P

From MGI

GO:0009967

positive regulation of signal transduction

MGI:MGI:3579197
PMID:15910753[4]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0010468

regulation of gene expression

MGI:MGI:3579197
PMID:15910753[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010468

regulation of gene expression

MGI:MGI:85084
PMID:9008714[5]

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0030501

positive regulation of bone mineralization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0030819

positive regulation of cAMP biosynthetic process

MGI:MGI:4358631
PMID:19723499[6]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030819

positive regulation of cAMP biosynthetic process

MGI:MGI:85084
PMID:9008714[5]

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0031856

parathyroid hormone receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P04089

F

From MGI

GO:0034645

cellular macromolecule biosynthetic process

MGI:MGI:4358631
PMID:19723499[6]

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0045725

positive regulation of glycogen biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3579197
PMID:15910753[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:4358631
PMID:19723499[6]

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0046326

positive regulation of glucose import

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

P

From MGI

GO:0051428

peptide hormone receptor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01270

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Kovacs CS et al. (2001) PTH regulates fetal blood calcium and skeletal mineralization independently of PTHrP. Endocrinology 142: 4983-93 PubMed GONUTS page
  2. Kabe Y et al. (2005) NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes. Mol Cell Biol 25: 512-22 PubMed GONUTS page
  3. Hoff AO et al. (2002) Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene. J Clin Invest 110: 1849-57 PubMed GONUTS page
  4. 4.0 4.1 4.2 Pirih FQ et al. (2005) Parathyroid hormone induces the NR4A family of nuclear orphan receptors in vivo. Biochem Biophys Res Commun 332: 494-503 PubMed GONUTS page
  5. 5.0 5.1 Amling M et al. (1997) Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development. J Cell Biol 136: 205-13 PubMed GONUTS page
  6. 6.0 6.1 6.2 Terauchi M et al. (2009) T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling. Cell Metab 10: 229-40 PubMed GONUTS page
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