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MGI:Ptges

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Ptges ( synonyms: D2Ertd369e, mPGES, mPGES-1 )
Protein Name(s) prostaglandin E synthase,
External Links
MGI MGI:1927593

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001516

prostaglandin biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_067594

P

From MGI

GO:0001516

prostaglandin biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O14684

P

From MGI

GO:0004667

prostaglandin-D synthase activity

MGI:MGI:2181910
PMID:12021206[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005641

nuclear envelope lumen

MGI:MGI:1913155
PMID:10869354[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2181910
PMID:12021206[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005792

microsome

MGI:MGI:2181910
PMID:12021206[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005792

microsome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_067594

C

From MGI

GO:0006633

fatty acid biosynthetic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0275

P

From MGI

GO:0006693

prostaglandin metabolic process

MGI:MGI:1913155
PMID:10869354[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008285

negative regulation of cell proliferation

MGI:MGI:3797426
PMID:18485889[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:88039

P

From MGI

GO:0008610

lipid biosynthetic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0444

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O14684

C

From MGI

GO:0016853

isomerase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0413

F

From MGI

GO:0043295

glutathione binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O14684

F

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_067594

C

From MGI

GO:0050220

prostaglandin-E synthase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_067594

F

From MGI

GO:0050220

prostaglandin-E synthase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O14684

F

From MGI

NOT

GO:0005634

nucleus

MGI:MGI:2181910
PMID:12021206[1]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Lazarus M et al. (2002) Immunohistochemical localization of microsomal PGE synthase-1 and cyclooxygenases in male mouse reproductive organs. Endocrinology 143: 2410-9 PubMed GONUTS page
  2. 2.0 2.1 Murakami M et al. (2000) Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J Biol Chem 275: 32783-92 PubMed GONUTS page
  3. Elander N et al. (2008) Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. Biochem Biophys Res Commun 372: 249-53 PubMed GONUTS page
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