MGI:Ptch1

From GONUTS

Jump to: navigation, search

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0001658	branching involved in ureteric bud morphogenesis	MGI:MGI:4367286 PMID:19809516^[1]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0001841	neural tube formation	MGI:MGI:3687672 PMID:10500113^[2]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0001843	neural tube closure	MGI:MGI:1095757 PMID:9262482^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0003007	heart morphogenesis	MGI:MGI:1095757 PMID:9262482^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0004872	receptor activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0675	F	From MGI
	GO:0005113	patched binding	MGI:MGI:3687672 PMID:10500113^[2]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0005119	smoothened binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3687672 PMID:10500113^[2]	IPI: Inferred from Physical Interaction	UniProtKB:Q62226	F	From MGI
	GO:0005576	extracellular region	MGI:MGI:3687672 PMID:10500113^[2]	TAS: Traceable Author Statement		C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:5306326 PMID:11331587^[4]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005886	plasma membrane	MGI:MGI:5306540 PMID:21931618^[5]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005887	integral to plasma membrane	MGI:MGI:2152606 PMID:11784021^[6]	TAS: Traceable Author Statement		C	From MGI
	GO:0005901	caveola	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	C	From MGI
	GO:0007165	signal transduction	MGI:MGI:3687672 PMID:10500113^[2]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0007224	smoothened signaling pathway	MGI:MGI:2135612 PMID:11493558^[7]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0007224	smoothened signaling pathway	MGI:MGI:3051703 PMID:15269168^[8]	IGI: Inferred from Genetic Interaction	MGI:MGI:1916147	P	From MGI
	GO:0007224	smoothened signaling pathway	MGI:MGI:85754 PMID:9006067^[9]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0007346	regulation of mitotic cell cycle	MGI:MGI:3619173 PMID:16489008^[10]	IMP: Inferred from Mutant Phenotype	MGI:MGI:2675356	P	From MGI
	GO:0007389	pattern specification process	MGI:MGI:1095757 PMID:9262482^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0007420	brain development	MGI:MGI:5142377 PMID:11517919^[11]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0008158	hedgehog receptor activity	MGI:MGI:2152606 PMID:11784021^[6]	TAS: Traceable Author Statement		F	From MGI
	GO:0008201	heparin binding	MGI:MGI:3687672 PMID:10500113^[2]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0008270	zinc ion binding	MGI:MGI:3687672 PMID:10500113^[2]	NAS: Non-traceable Author Statement		F	From MGI
	GO:0008285	negative regulation of cell proliferation	MGI:MGI:3619173 PMID:16489008^[10]	IMP: Inferred from Mutant Phenotype	MGI:MGI:2675356	P	From MGI
	GO:0008285	negative regulation of cell proliferation	MGI:MGI:5306326 PMID:11331587^[4]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0008544	epidermis development	MGI:MGI:3721205 PMID:17631878^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856954	P	From MGI
	GO:0008589	regulation of smoothened signaling pathway	MGI:MGI:2152606 PMID:11784021^[6]	IMP: Inferred from Mutant Phenotype	MGI:MGI:2153143	P	From MGI
	GO:0008589	regulation of smoothened signaling pathway	MGI:MGI:3821640 PMID:19004860^[13]	IGI: Inferred from Genetic Interaction	MGI:MGI:2142166	P	From MGI
	GO:0009887	organ morphogenesis	MGI:MGI:2675247 PMID:12917290^[14]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0009953	dorsal/ventral pattern formation	MGI:MGI:3511726 PMID:15576403^[15]	IGI: Inferred from Genetic Interaction	MGI:MGI:1341847	P	From MGI
	GO:0010157	response to chlorate	MGI:MGI:2149274 PMID:11476578^[16]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0010875	positive regulation of cholesterol efflux	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0014069	postsynaptic density	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	NCBI:NP_446018	C	From MGI
	GO:0015485	cholesterol binding	MGI:MGI:3687672 PMID:10500113^[2]	TAS: Traceable Author Statement		F	From MGI
	GO:0015485	cholesterol binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	F	From MGI
	GO:0016020	membrane	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0472	C	From MGI
	GO:0016020	membrane	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR003392	C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0812	C	From MGI
	GO:0016021	integral to membrane	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR000731 InterPro:IPR004766	C	From MGI
	GO:0016485	protein processing	MGI:MGI:3588600 PMID:16061793^[17]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0021532	neural tube patterning	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0021904	dorsal/ventral neural tube patterning	MGI:MGI:1095757 PMID:9262482^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0021997	neural plate axis specification	MGI:MGI:5142377 PMID:11517919^[11]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0030326	embryonic limb morphogenesis	MGI:MGI:2135419 PMID:11389830^[18]	IGI: Inferred from Genetic Interaction	MGI:MGI:98297	P	From MGI
	GO:0030326	embryonic limb morphogenesis	MGI:MGI:2152606 PMID:11784021^[6]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856954	P	From MGI
	GO:0030332	cyclin binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	F	From MGI
	GO:0030332	cyclin binding	MGI:MGI:5306326 PMID:11331587^[4]	IPI: Inferred from Physical Interaction	UniProtKB:P13350	F	From MGI
	GO:0030496	midbody	MGI:MGI:4942244 PMID:15166316^[19]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0030879	mammary gland development	MGI:MGI:1346456 PMID:10529434^[20]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0032403	protein complex binding	MGI:MGI:5306326 PMID:11331587^[4]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0032880	regulation of protein localization	MGI:MGI:3619173 PMID:16489008^[10]	IMP: Inferred from Mutant Phenotype	MGI:MGI:2675356	P	From MGI
	GO:0032880	regulation of protein localization	MGI:MGI:5306326 PMID:11331587^[4]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0035108	limb morphogenesis	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0035137	hindlimb morphogenesis	MGI:MGI:1095757 PMID:9262482^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0040008	regulation of growth	MGI:MGI:1095757 PMID:9262482^[3]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0040015	negative regulation of multicellular organism growth	MGI:MGI:2152606 PMID:11784021^[6]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856954	P	From MGI
	GO:0042127	regulation of cell proliferation	MGI:MGI:4367286 PMID:19809516^[1]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0042593	glucose homeostasis	MGI:MGI:1926239 PMID:11044404^[21]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0043231	intracellular membrane-bounded organelle	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	C	From MGI
	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0043616	keratinocyte proliferation	MGI:MGI:3721205 PMID:17631878^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856954	P	From MGI
	GO:0044294	dendritic growth cone	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	NCBI:NP_446018	C	From MGI
	GO:0044295	axonal growth cone	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	NCBI:NP_446018	C	From MGI
	GO:0045668	negative regulation of osteoblast differentiation	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0045879	negative regulation of smoothened signaling pathway	MGI:MGI:4367286 PMID:19809516^[1]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0045879	negative regulation of smoothened signaling pathway	MGI:MGI:5142377 PMID:11517919^[11]	NAS: Non-traceable Author Statement		P	From MGI
	GO:0045879	negative regulation of smoothened signaling pathway	MGI:MGI:5306540 PMID:21931618^[5]	IGI: Inferred from Genetic Interaction	UniProtKB:Q62226	P	From MGI
	GO:0048471	perinuclear region of cytoplasm	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	C	From MGI
	GO:0050680	negative regulation of epithelial cell proliferation	MGI:MGI:3721205 PMID:17631878^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1856954	P	From MGI
	GO:0051782	negative regulation of cell division	MGI:MGI:5306326 PMID:11331587^[4]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0060037	pharyngeal system development	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0060603	mammary gland duct morphogenesis	MGI:MGI:1346456 PMID:10529434^[20]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0060644	mammary gland epithelial cell differentiation	MGI:MGI:1346456 PMID:10529434^[20]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0061005	cell differentiation involved in kidney development	MGI:MGI:4367286 PMID:19809516^[1]	IGI: Inferred from Genetic Interaction	MGI:MGI:95729	P	From MGI
	GO:0061053	somite development	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0061053	somite development	MGI:MGI:5142377 PMID:11517919^[11]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0071397	cellular response to cholesterol	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0072203	cell proliferation involved in metanephros development	MGI:MGI:4367286 PMID:19809516^[1]	IMP: Inferred from Mutant Phenotype	MGI:MGI:1857447	P	From MGI
	GO:0072661	protein targeting to plasma membrane	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	P	From MGI
	GO:0097108	hedgehog family protein binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:Q13635	F	From MGI
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Cain JE et al. (2009) GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One 4: e7313 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 Fuse N et al. (1999) Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched. Proc Natl Acad Sci U S A 96: 10992-9 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Goodrich LV et al. (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277: 1109-13 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Barnes EA et al. (2001) Patched1 interacts with cyclin B1 to regulate cell cycle progression. EMBO J 20: 2214-23 PubMed GONUTS page
↑ ^5.0 ^5.1 Bidet M et al. (2011) The hedgehog receptor patched is involved in cholesterol transport. PLoS One 6: e23834 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 Makino S et al. (2001) A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc). Dev Biol 239: 95-106 PubMed GONUTS page
↑ Mahlapuu M et al. (2001) Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations. Development 128: 2397-406 PubMed GONUTS page
↑ Tian H et al. (2004) Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development 131: 4021-33 PubMed GONUTS page
↑ Bellusci S et al. (1997) Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development 124: 53-63 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 Adolphe C et al. (2006) Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res 66: 2081-8 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 Zhang XM et al. (2001) Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell 106: 781-92 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 Nieuwenhuis E et al. (2007) Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1. Dev Biol 308: 547-60 PubMed GONUTS page
↑ Hoover AN et al. (2008) C2cd3 is required for cilia formation and Hedgehog signaling in mouse. Development 135: 4049-58 PubMed GONUTS page
↑ Kawahira H et al. (2003) Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development 130: 4871-9 PubMed GONUTS page
↑ Jeong J & McMahon AP (2005) Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development 132: 143-54 PubMed GONUTS page
↑ Gritli-Linde A et al. (2001) The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Dev Biol 236: 364-86 PubMed GONUTS page
↑ Huangfu D & Anderson KV (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-30 PubMed GONUTS page
↑ Lewis PM et al. (2001) Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105: 599-612 PubMed GONUTS page
↑ Skop AR et al. (2004) Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science 305: 61-6 PubMed GONUTS page
↑ ^20.0 ^20.1 ^20.2 Lewis MT et al. (1999) Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. Development 126: 5181-93 PubMed GONUTS page
↑ Hebrok M et al. (2000) Regulation of pancreas development by hedgehog signaling. Development 127: 4905-13 PubMed GONUTS page

[PMID:19809516-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Cain JE et al. (2009) GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One 4: e7313 PubMed GONUTS page

[PMID:10500113-1] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 Fuse N et al. (1999) Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched. Proc Natl Acad Sci U S A 96: 10992-9 PubMed GONUTS page

[PMID:9262482-2] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Goodrich LV et al. (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277: 1109-13 PubMed GONUTS page

[PMID:11331587-3] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 Barnes EA et al. (2001) Patched1 interacts with cyclin B1 to regulate cell cycle progression. EMBO J 20: 2214-23 PubMed GONUTS page

[PMID:21931618-4] 5.0 ^5.1 Bidet M et al. (2011) The hedgehog receptor patched is involved in cholesterol transport. PLoS One 6: e23834 PubMed GONUTS page

[PMID:11784021-5] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 Makino S et al. (2001) A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc). Dev Biol 239: 95-106 PubMed GONUTS page

[PMID:11493558-6] Mahlapuu M et al. (2001) Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations. Development 128: 2397-406 PubMed GONUTS page

[PMID:15269168-7] Tian H et al. (2004) Dose dependency of Disp1 and genetic interaction between Disp1 and other hedgehog signaling components in the mouse. Development 131: 4021-33 PubMed GONUTS page

[PMID:9006067-8] Bellusci S et al. (1997) Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development 124: 53-63 PubMed GONUTS page

[PMID:16489008-9] 10.0 ^10.1 ^10.2 Adolphe C et al. (2006) Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res 66: 2081-8 PubMed GONUTS page

[PMID:11517919-10] 11.0 ^11.1 ^11.2 ^11.3 Zhang XM et al. (2001) Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell 106: 781-92 PubMed GONUTS page

[PMID:17631878-11] 12.0 ^12.1 ^12.2 Nieuwenhuis E et al. (2007) Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1. Dev Biol 308: 547-60 PubMed GONUTS page

[PMID:19004860-12] Hoover AN et al. (2008) C2cd3 is required for cilia formation and Hedgehog signaling in mouse. Development 135: 4049-58 PubMed GONUTS page

[PMID:12917290-13] Kawahira H et al. (2003) Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development 130: 4871-9 PubMed GONUTS page

[PMID:15576403-14] Jeong J & McMahon AP (2005) Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development 132: 143-54 PubMed GONUTS page

[PMID:11476578-15] Gritli-Linde A et al. (2001) The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Dev Biol 236: 364-86 PubMed GONUTS page

[PMID:16061793-16] Huangfu D & Anderson KV (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-30 PubMed GONUTS page

[PMID:11389830-17] Lewis PM et al. (2001) Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105: 599-612 PubMed GONUTS page

[PMID:15166316-18] Skop AR et al. (2004) Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science 305: 61-6 PubMed GONUTS page

[PMID:10529434-19] 20.0 ^20.1 ^20.2 Lewis MT et al. (1999) Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. Development 126: 5181-93 PubMed GONUTS page

[PMID:11044404-20] Hebrok M et al. (2000) Regulation of pancreas development by hedgehog signaling. Development 127: 4905-13 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

[19]

[20]

[21]

Species (Taxon ID)	Mus musculus (house mouse) (taxon:10090)
Gene Name(s)	Ptch1 ( synonyms: Patched 1, Ptc, Ptc1 )
Protein Name(s)	patched homolog 1,
External Links
MGI	MGI:105373

MGI:Ptch1

Contents

Annotations

Notes

References

a

b

c

d

e

f

g

h

h cont.

i

k

l

m

n

n cont.

o

p

r

s

t

v

z

Personal tools

Namespaces

Variants

Views

Actions

Search

Navigation

Cacao

Journal Clubs

page contributors

Toolbox