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MGI:Prrx2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Prrx2 ( synonyms: Prx2, S8 ) | |
| Protein Name(s) | paired related homeobox 2, | |
| External Links | ||
| MGI | MGI:98218 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002053 |
positive regulation of mesenchymal cell proliferation |
MGI:MGI:2149056 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0238 |
F |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0030326 |
embryonic limb morphogenesis |
MGI:MGI:1306737 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0030326 |
embryonic limb morphogenesis |
MGI:MGI:1328643 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0042472 |
inner ear morphogenesis |
MGI:MGI:1306737 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0042474 |
middle ear morphogenesis |
MGI:MGI:1306737 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0045880 |
positive regulation of smoothened signaling pathway |
MGI:MGI:2149056 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0048701 |
embryonic cranial skeleton morphogenesis |
MGI:MGI:1306737 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0048704 |
embryonic skeletal system morphogenesis |
MGI:MGI:1306737 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0048704 |
embryonic skeletal system morphogenesis |
MGI:MGI:1321048 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0048704 |
embryonic skeletal system morphogenesis |
MGI:MGI:2149056 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0048844 |
artery morphogenesis |
MGI:MGI:1353388 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0051216 |
cartilage development |
MGI:MGI:1321048 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97712 |
P |
From MGI |
||
| GO:0071837 |
HMG box domain binding |
MGI:MGI:5284787 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 ten Berge D et al. (2001) Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis. Development 128: 2929-38 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 ten Berge D et al. (1998) Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs. Development 125: 3831-42 PubMed GONUTS page
- ↑ Lu MF et al. (1999) Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Dev Biol 205: 145-57 PubMed GONUTS page
- ↑ 4.0 4.1 Lu MF et al. (1999) prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme. Development 126: 495-504 PubMed GONUTS page
- ↑ Bergwerff M et al. (2000) Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus. Virchows Arch 436: 12-9 PubMed GONUTS page
- ↑ Wissmüller S et al. (2006) The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Nucleic Acids Res 34: 1735-44 PubMed GONUTS page
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