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MGI:Prl

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Prl ( synonyms: Prl, Prl1a1 )
Protein Name(s) prolactin,
External Links
MGI MGI:97762

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005148

prolactin receptor binding

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P01240

F

From MGI

GO:0005179

hormone activity

MGI:MGI:2386424
PMID:12147240[1]

TAS: Traceable Author Statement

F

From MGI

GO:0005576

extracellular region

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01237

C

From MGI

GO:0007262

STAT protein import into nucleus

MGI:MGI:2386424
PMID:12147240[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01237

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:894560
PMID:9247268[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:94924

P

From MGI

GO:0030141

secretory granule

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01237

C

From MGI

GO:0030141

secretory granule

MGI:MGI:894561
PMID:9247267[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0030278

regulation of ossification

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01237

P

From MGI

GO:0030879

mammary gland development

MGI:MGI:3799386
PMID:18425773[4]

IGI: Inferred from Genetic Interaction

MGI:MGI:105088

P

From MGI

GO:0046425

regulation of JAK-STAT cascade

MGI:MGI:2386424
PMID:12147240[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046427

positive regulation of JAK-STAT cascade

MGI:MGI:3703676
PMID:12388746[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:102709

P

From MGI

GO:0046427

positive regulation of JAK-STAT cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P01236

P

From MGI

GO:0050679

positive regulation of epithelial cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01237

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Olsen H et al. (2002) Effects of hyperactive Janus kinase 2 signaling in mammary epithelial cells. Biochem Biophys Res Commun 296: 139-44 PubMed GONUTS page
  2. Saiardi A et al. (1997) Antiproliferative role of dopamine: loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia. Neuron 19: 115-26 PubMed GONUTS page
  3. Kelly MA et al. (1997) Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron 19: 103-13 PubMed GONUTS page
  4. Strizzi L et al. (2008) Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland. J Cell Physiol 216: 824-34 PubMed GONUTS page
  5. Park DS et al. (2002) Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. Mol Biol Cell 13: 3416-30 PubMed GONUTS page
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