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MGI:Prkra
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Prkra ( synonyms: lear, Pact, PRK, RAX ) | |
| Protein Name(s) | protein kinase, interferon inducible double stranded RNA dependent activator, | |
| External Links | ||
| MGI | MGI:1344375 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0003723 |
RNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003725 |
double-stranded RNA binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3843425 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3623660 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:1337946 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:2386461 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006950 |
response to stress |
MGI:MGI:1337946 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From MGI |
||
| GO:0016310 |
phosphorylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From MGI |
||
| GO:0030422 |
production of siRNA involved in RNA interference |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031047 |
gene silencing by RNA |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0943 |
P |
From MGI |
||
| GO:0042473 |
outer ear morphogenesis |
MGI:MGI:3623660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3626341 |
P |
From MGI |
||
| GO:0042474 |
middle ear morphogenesis |
MGI:MGI:3623660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3626341 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0048705 |
skeletal system morphogenesis |
MGI:MGI:3623660 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3626341 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kok KH et al. (2007) Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. J Biol Chem 282: 17649-57 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Rowe TM et al. (2006) A role of the double-stranded RNA-binding protein PACT in mouse ear development and hearing. Proc Natl Acad Sci U S A 103: 5823-8 PubMed GONUTS page
- ↑ 3.0 3.1 Ito T et al. (1999) RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. J Biol Chem 274: 15427-32 PubMed GONUTS page
- ↑ Gupta V & Patel RC (2002) Proapoptotic protein PACT is expressed at high levels in colonic epithelial cells in mice. Am J Physiol Gastrointest Liver Physiol 283: G801-8 PubMed GONUTS page
