GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Ppp2cb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ppp2cb ( synonyms: D8Ertd766e, PP2Ac ) | |
| Protein Name(s) | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform, | |
| External Links | ||
| MGI | MGI:1321161 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000159 |
protein phosphatase type 2A complex |
MGI:MGI:3694309 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000775 |
chromosome, centromeric region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0137 |
C |
From MGI |
||
| GO:0004721 |
phosphoprotein phosphatase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2669024 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3694309 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1858324 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005694 |
chromosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0158 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:1858324 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008022 |
protein C-terminus binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0010468 |
regulation of gene expression |
MGI:MGI:3694309 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0042221 |
response to chemical stimulus |
MGI:MGI:3694309 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042542 |
response to hydrogen peroxide |
MGI:MGI:3694309 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:3694309 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043161 |
proteasomal ubiquitin-dependent protein catabolic process |
MGI:MGI:3694309 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046580 |
negative regulation of Ras protein signal transduction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046677 |
response to antibiotic |
MGI:MGI:3694309 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Lin SS et al. (2006) PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum. J Biol Chem 281: 23003-12 PubMed GONUTS page
- ↑ Yoshinari K et al. (2003) Identification of the nuclear receptor CAR:HSP90 complex in mouse liver and recruitment of protein phosphatase 2A in response to phenobarbital. FEBS Lett 548: 17-20 PubMed GONUTS page
- ↑ 3.0 3.1 Götz J et al. (2000) Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development. Mech Dev 93: 83-93 PubMed GONUTS page
