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MGI:Ppp1r1b
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ppp1r1b ( synonyms: DARPP-32, Darpp32 ) | |
| Protein Name(s) | protein phosphatase 1, regulatory (inhibitor) subunit 1B, | |
| External Links | ||
| MGI | MGI:94860 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001975 |
response to amphetamine |
MGI:MGI:3761427 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97523 |
P |
From MGI |
||
| GO:0004864 |
protein phosphatase inhibitor activity |
MGI:MGI:1859689 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004865 |
protein serine/threonine phosphatase inhibitor activity |
MGI:MGI:1289105 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004865 |
protein serine/threonine phosphatase inhibitor activity |
MGI:MGI:48590 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005102 |
receptor binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_612530 |
F |
From MGI |
||
| GO:0005622 |
intracellular |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_612530 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:3797712 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3797712 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:48590 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1859689 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007621 |
negative regulation of female receptivity |
MGI:MGI:1353196 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007621 |
negative regulation of female receptivity |
MGI:MGI:1353196 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008542 |
visual learning |
MGI:MGI:3761427 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:97523 |
P |
From MGI |
||
| GO:0035556 |
intracellular signal transduction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_612530 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Ehrman LA et al. (2006) Phosphodiesterase 1B differentially modulates the effects of methamphetamine on locomotor activity and spatial learning through DARPP32-dependent pathways: evidence from PDE1B-DARPP32 double-knockout mice. Genes Brain Behav 5: 540-51 PubMed GONUTS page
- ↑ 2.0 2.1 Svenningsson P et al. (2000) Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32. J Neurochem 75: 248-57 PubMed GONUTS page
- ↑ Blau S et al. (1995) DARPP-32 promoter directs transgene expression to renal thick ascending limb of loop of Henle. Am J Physiol 269: F564-70 PubMed GONUTS page
- ↑ 4.0 4.1 Perez RG & Lewis RM (1992) Regional distribution of DARPP-32 (dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein of Mr = 32,000) mRNA in mouse brain. J Comp Neurol 318: 304-15 PubMed GONUTS page
- ↑ 5.0 5.1 Stipanovich A et al. (2008) A phosphatase cascade by which rewarding stimuli control nucleosomal response. Nature 453: 879-84 PubMed GONUTS page
- ↑ 6.0 6.1 Mani SK et al. (2000) Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice. Science 287: 1053-6 PubMed GONUTS page
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