![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Ppp1ca
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ppp1ca ( synonyms: dism2, Ppp1c ) | |
| Protein Name(s) | protein phosphatase 1, catalytic subunit, alpha isoform, | |
| External Links | ||
| MGI | MGI:103016 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000164 |
protein phosphatase type 1 complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0004721 |
phosphoprotein phosphatase activity |
MGI:MGI:2679135 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004721 |
phosphoprotein phosphatase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:1327477 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:2183839 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:3028820 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:70347 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
MGI:MGI:73007 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3709531 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5000151 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5000151 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:5000151 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005654 |
nucleoplasm |
MGI:MGI:1327477 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005654 |
nucleoplasm |
MGI:MGI:3039057 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:1327477 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3039057 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:5000151 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005975 |
carbohydrate metabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0119 |
P |
From MGI |
||
| GO:0005977 |
glycogen metabolic process |
MGI:MGI:73007 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0005979 |
regulation of glycogen biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005981 |
regulation of glycogen catabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006417 |
regulation of translation |
MGI:MGI:73007 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:1327477 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:2679135 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:3028820 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006470 |
protein dephosphorylation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007143 |
female meiosis |
MGI:MGI:1327477 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0008152 |
metabolic process |
MGI:MGI:73007 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0009987 |
cellular process |
MGI:MGI:70347 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0016787 |
hydrolase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030324 |
lung development |
MGI:MGI:3039057 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042587 |
glycogen granule |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043005 |
neuron projection |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043021 |
ribonucleoprotein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043197 |
dendritic spine |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043204 |
perikaryon |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048754 |
branching morphogenesis of a tube |
MGI:MGI:3039057 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051301 |
cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From MGI |
||
| GO:0070688 |
MLL5-L complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0072357 |
PTW/PP1 phosphatase complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kissil JL et al. (2003) Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Mol Cell 12: 841-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Smith GD et al. (1998) Characterization of protein phosphatases in mouse oocytes. Dev Biol 204: 537-49 PubMed GONUTS page
- ↑ Ayllón V et al. (2002) The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad. Eur J Immunol 32: 1847-55 PubMed GONUTS page
- ↑ 4.0 4.1 Llorian M et al. (2004) SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1. Biochem J 378: 229-38 PubMed GONUTS page
- ↑ 5.0 5.1 Saadat M et al. (1994) Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization. Jpn J Genet 69: 697-700 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Saadat M et al. (1995) Comparative mapping of the gene encoding the catalytic subunit of protein phosphatase type 1 alpha (PPP1CA) to human, rat, and mouse chromosomes. Cytogenet Cell Genet 70: 55-7 PubMed GONUTS page
- ↑ Flores-Delgado G et al. (2007) A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis. J Proteome Res 6: 1165-75 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 Luo X et al. (2011) Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis. Diabetes 60: 1435-45 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Hormi-Carver KK et al. (2004) Protein phosphatase 1alpha is required for murine lung growth and morphogenesis. Dev Dyn 229: 791-801 PubMed GONUTS page