MGI:Pparg

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	MGI:MGI:3604169 PMID:16127449^[1]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	MGI:MGI:67592 PMID:8041794^[2]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0001012	RNA polymerase II regulatory region DNA binding	MGI:MGI:3050916 PMID:15175325^[3]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0001818	negative regulation of cytokine production	MGI:MGI:3799438 PMID:18566389^[4]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0001890	placenta development	MGI:MGI:3769865 PMID:17463056^[5]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0002674	negative regulation of acute inflammatory response	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0003677	DNA binding	MGI:MGI:2180395 PMID:12037571^[6]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3529655 PMID:15681609^[7]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003677	DNA binding	MGI:MGI:3529655 PMID:15681609^[7]	IPI: Inferred from Physical Interaction	UniProtKB:P28700	F	From MGI
	GO:0003677	DNA binding	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	F	From MGI
	GO:0003677	DNA binding	MGI:MGI:67592 PMID:8041794^[2]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003682	chromatin binding	MGI:MGI:3821921 PMID:19066220^[8]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003700	sequence-specific DNA binding transcription factor activity	MGI:MGI:2180395 PMID:12037571^[6]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0003700	sequence-specific DNA binding transcription factor activity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	F	From MGI
	GO:0003700	sequence-specific DNA binding transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0003707	steroid hormone receptor activity	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR008946 InterPro:IPR000536 InterPro:IPR001723	F	From MGI
	GO:0004872	receptor activity	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0675	F	From MGI
	GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	MGI:MGI:2384214 PMID:12163159^[9]	TAS: Traceable Author Statement		F	From MGI
	GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3604169 PMID:16127449^[1]	IPI: Inferred from Physical Interaction	UniProtKB:O88907	F	From MGI
	GO:0005515	protein binding	MGI:MGI:3806432 PMID:18719582^[10]	IPI: Inferred from Physical Interaction	UniProtKB:A2A935	F	From MGI
	GO:0005634	nucleus	MGI:MGI:2384214 PMID:12163159^[9]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:3045488 PMID:15164767^[11]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005634	nucleus	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	C	From MGI
	GO:0005634	nucleus	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	C	From MGI
	GO:0005737	cytoplasm	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0963	C	From MGI
	GO:0005829	cytosol	MGI:MGI:2384214 PMID:12163159^[9]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005829	cytosol	MGI:MGI:3045488 PMID:15164767^[11]	IDA: Inferred from Direct Assay		C	From MGI
	GO:0005829	cytosol	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	C	From MGI
	GO:0006351	transcription, DNA-dependent	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0804	P	From MGI
	GO:0006355	regulation of transcription, DNA-dependent	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0805	P	From MGI
	GO:0006355	regulation of transcription, DNA-dependent	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR003074 InterPro:IPR003077 InterPro:IPR008946 InterPro:IPR000536 InterPro:IPR001723 InterPro:IPR001628 InterPro:IPR013088	P	From MGI
	GO:0006357	regulation of transcription from RNA polymerase II promoter	MGI:MGI:2384214 PMID:12163159^[9]	TAS: Traceable Author Statement		P	From MGI
	GO:0006917	induction of apoptosis	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0006954	inflammatory response	MGI:MGI:2384214 PMID:12163159^[9]	TAS: Traceable Author Statement		P	From MGI
	GO:0007165	signal transduction	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0008144	drug binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0008217	regulation of blood pressure	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0008270	zinc ion binding	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR001628 InterPro:IPR013088	F	From MGI
	GO:0008285	negative regulation of cell proliferation	MGI:MGI:2388776 PMID:12370429^[12]	IMP: Inferred from Mutant Phenotype	MGI:MGI:2384321	P	From MGI
	GO:0008285	negative regulation of cell proliferation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0010745	negative regulation of macrophage derived foam cell differentiation	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0010871	negative regulation of receptor biosynthetic process	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0010887	negative regulation of cholesterol storage	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0010891	negative regulation of sequestering of triglyceride	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0015909	long-chain fatty acid transport	MGI:MGI:3769865 PMID:17463056^[5]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0019216	regulation of lipid metabolic process	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0019395	fatty acid oxidation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0019899	enzyme binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0030224	monocyte differentiation	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0030308	negative regulation of cell growth	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0030522	intracellular receptor mediated signaling pathway	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0030855	epithelial cell differentiation	MGI:MGI:3527921 PMID:15687259^[13]	IGI: Inferred from Genetic Interaction	MGI:MGI:102784	P	From MGI
	GO:0032869	cellular response to insulin stimulus	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0033613	activating transcription factor binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0033993	response to lipid	MGI:MGI:3793920 PMID:9568715^[14]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0042593	glucose homeostasis	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0042953	lipoprotein transport	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0043401	steroid hormone mediated signaling pathway	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR008946 InterPro:IPR000536	P	From MGI
	GO:0043565	sequence-specific DNA binding	MGI:MGI:2152098	IEA: Inferred from Electronic Annotation	InterPro:IPR001628	F	From MGI
	GO:0044212	transcription regulatory region DNA binding	MGI:MGI:3604169 PMID:16127449^[1]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0044212	transcription regulatory region DNA binding	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	F	From MGI
	GO:0044212	transcription regulatory region DNA binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0045165	cell fate commitment	MGI:MGI:3527921 PMID:15687259^[13]	IGI: Inferred from Genetic Interaction	MGI:MGI:102784	P	From MGI
	GO:0045444	fat cell differentiation	MGI:MGI:2180395 PMID:12037571^[6]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045444	fat cell differentiation	MGI:MGI:2448203 PMID:12502791^[15]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045444	fat cell differentiation	MGI:MGI:3587162 PMID:16099986^[16]	IGI: Inferred from Genetic Interaction	MGI:MGI:1917649	P	From MGI
	GO:0045598	regulation of fat cell differentiation	MGI:MGI:3054887 PMID:12097321^[17]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045598	regulation of fat cell differentiation	MGI:MGI:3821921 PMID:19066220^[8]	IGI: Inferred from Genetic Interaction	MGI:MGI:1337080	P	From MGI
	GO:0045598	regulation of fat cell differentiation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0045600	positive regulation of fat cell differentiation	MGI:MGI:3050916 PMID:15175325^[3]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045600	positive regulation of fat cell differentiation	MGI:MGI:3574150 PMID:15728361^[18]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045600	positive regulation of fat cell differentiation	MGI:MGI:3758508 PMID:10937998^[19]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045600	positive regulation of fat cell differentiation	MGI:MGI:3770601 PMID:17905753^[20]	IGI: Inferred from Genetic Interaction	MGI:MGI:1096393	P	From MGI
	GO:0045600	positive regulation of fat cell differentiation	MGI:MGI:3821921 PMID:19066220^[8]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0045892	negative regulation of transcription, DNA-dependent	MGI:MGI:3529655 PMID:15681609^[7]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0045892	negative regulation of transcription, DNA-dependent	MGI:MGI:3529655 PMID:15681609^[7]	IMP: Inferred from Mutant Phenotype		P	From MGI
	GO:0045892	negative regulation of transcription, DNA-dependent	MGI:MGI:3604169 PMID:16127449^[1]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:3032469 PMID:14744933^[21]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045893	positive regulation of transcription, DNA-dependent	MGI:MGI:3578695 PMID:15684432^[22]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:MGI:2180395 PMID:12037571^[6]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:MGI:3587162 PMID:16099986^[16]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:MGI:3604169 PMID:16127449^[1]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0045944	positive regulation of transcription from RNA polymerase II promoter	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0046321	positive regulation of fatty acid oxidation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0046872	metal ion binding	MGI:MGI:1354194	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0479	F	From MGI
	GO:0046965	retinoid X receptor binding	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	F	From MGI
	GO:0048469	cell maturation	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0048714	positive regulation of oligodendrocyte differentiation	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0050544	arachidonic acid binding	MGI:MGI:3793920 PMID:9568715^[14]	IDA: Inferred from Direct Assay		F	From MGI
	GO:0050872	white fat cell differentiation	MGI:MGI:3801349 PMID:18492766^[23]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0050873	brown fat cell differentiation	MGI:MGI:3801349 PMID:18492766^[23]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0051974	negative regulation of telomerase activity	MGI:MGI:4417868	ISO: Inferred from Sequence Orthology	UniProtKB:O88275	P	From MGI
	GO:0055098	response to low-density lipoprotein particle stimulus	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0060336	negative regulation of interferon-gamma-mediated signaling pathway	MGI:MGI:4834177	ISO: Inferred from Sequence Orthology	UniProtKB:P37231	P	From MGI
	GO:0071285	cellular response to lithium ion	MGI:MGI:3581945 PMID:15673614^[24]	IDA: Inferred from Direct Assay		P	From MGI
	GO:0071407	cellular response to organic cyclic compound	MGI:MGI:2385552 PMID:12055200^[25]	IDA: Inferred from Direct Assay		P	From MGI
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Pascual G et al. (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437: 759-63 PubMed GONUTS page
↑ ^2.0 ^2.1 Kliewer SA et al. (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A 91: 7355-9 PubMed GONUTS page
↑ ^3.0 ^3.1 Ichida F et al. (2004) Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation. J Biol Chem 279: 34015-22 PubMed GONUTS page
↑ Bonfield TL et al. (2008) Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor. J Immunol 181: 235-42 PubMed GONUTS page
↑ ^5.0 ^5.1 Schaiff WT et al. (2007) Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice. Endocrinology 148: 3625-34 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Ge K et al. (2002) Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature 417: 563-7 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Guan HP et al. (2005) Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev 19: 453-61 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Nofsinger RR et al. (2008) SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proc Natl Acad Sci U S A 105: 20021-6 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 ^9.4 Shibuya A et al. (2002) Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264. FEBS Lett 525: 43-7 PubMed GONUTS page
↑ Seale P et al. (2008) PRDM16 controls a brown fat/skeletal muscle switch. Nature 454: 961-7 PubMed GONUTS page
↑ ^11.0 ^11.1 Guthmann F et al. (2004) Phenotype of palmitic acid transport and of signalling in alveolar type II cells from E/H-FABP double-knockout mice: contribution of caveolin-1 and PPARgamma. Biochim Biophys Acta 1636: 196-204 PubMed GONUTS page
↑ Girnun GD et al. (2002) APC-dependent suppression of colon carcinogenesis by PPARgamma. Proc Natl Acad Sci U S A 99: 13771-6 PubMed GONUTS page
↑ ^13.0 ^13.1 Drori S et al. (2005) Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev 19: 362-75 PubMed GONUTS page
↑ ^14.0 ^14.1 Nagy L et al. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 93: 229-40 PubMed GONUTS page
↑ Tang QQ et al. (2003) Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci U S A 100: 44-9 PubMed GONUTS page
↑ ^16.0 ^16.1 Hong JH et al. (2005) TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 309: 1074-8 PubMed GONUTS page
↑ Gray S et al. (2002) The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. J Biol Chem 277: 34322-8 PubMed GONUTS page
↑ Bennett CN et al. (2005) Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A 102: 3324-9 PubMed GONUTS page
↑ Ross SE et al. (2000) Inhibition of adipogenesis by Wnt signaling. Science 289: 950-3 PubMed GONUTS page
↑ Pérez-Mancera PA et al. (2007) Adipose tissue mass is modulated by SLUG (SNAI2). Hum Mol Genet 16: 2972-86 PubMed GONUTS page
↑ Fan M et al. (2004) Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev 18: 278-89 PubMed GONUTS page
↑ Makowski L et al. (2005) The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. J Biol Chem 280: 12888-95 PubMed GONUTS page
↑ ^23.0 ^23.1 Wu Y & Smas CM (2008) Wdnm1-like, a new adipokine with a role in MMP-2 activation. Am J Physiol Endocrinol Metab 295: E205-15 PubMed GONUTS page
↑ Vertino AM et al. (2005) Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell 16: 2039-48 PubMed GONUTS page
↑ Bennett CN et al. (2002) Regulation of Wnt signaling during adipogenesis. J Biol Chem 277: 30998-1004 PubMed GONUTS page

[PMID:16127449-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Pascual G et al. (2005) A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma. Nature 437: 759-63 PubMed GONUTS page

[PMID:8041794-1] 2.0 ^2.1 Kliewer SA et al. (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A 91: 7355-9 PubMed GONUTS page

[PMID:15175325-2] 3.0 ^3.1 Ichida F et al. (2004) Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation. J Biol Chem 279: 34015-22 PubMed GONUTS page

[PMID:18566389-3] Bonfield TL et al. (2008) Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor. J Immunol 181: 235-42 PubMed GONUTS page

[PMID:17463056-4] 5.0 ^5.1 Schaiff WT et al. (2007) Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice. Endocrinology 148: 3625-34 PubMed GONUTS page

[PMID:12037571-5] 6.0 ^6.1 ^6.2 ^6.3 Ge K et al. (2002) Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature 417: 563-7 PubMed GONUTS page

[PMID:15681609-6] 7.0 ^7.1 ^7.2 ^7.3 Guan HP et al. (2005) Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes. Genes Dev 19: 453-61 PubMed GONUTS page

[PMID:19066220-7] 8.0 ^8.1 ^8.2 Nofsinger RR et al. (2008) SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proc Natl Acad Sci U S A 105: 20021-6 PubMed GONUTS page

[PMID:12163159-8] 9.0 ^9.1 ^9.2 ^9.3 ^9.4 Shibuya A et al. (2002) Nitration of PPARgamma inhibits ligand-dependent translocation into the nucleus in a macrophage-like cell line, RAW 264. FEBS Lett 525: 43-7 PubMed GONUTS page

[PMID:18719582-9] Seale P et al. (2008) PRDM16 controls a brown fat/skeletal muscle switch. Nature 454: 961-7 PubMed GONUTS page

[PMID:15164767-10] 11.0 ^11.1 Guthmann F et al. (2004) Phenotype of palmitic acid transport and of signalling in alveolar type II cells from E/H-FABP double-knockout mice: contribution of caveolin-1 and PPARgamma. Biochim Biophys Acta 1636: 196-204 PubMed GONUTS page

[PMID:12370429-11] Girnun GD et al. (2002) APC-dependent suppression of colon carcinogenesis by PPARgamma. Proc Natl Acad Sci U S A 99: 13771-6 PubMed GONUTS page

[PMID:15687259-12] 13.0 ^13.1 Drori S et al. (2005) Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev 19: 362-75 PubMed GONUTS page

[PMID:9568715-13] 14.0 ^14.1 Nagy L et al. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 93: 229-40 PubMed GONUTS page

[PMID:12502791-14] Tang QQ et al. (2003) Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci U S A 100: 44-9 PubMed GONUTS page

[PMID:16099986-15] 16.0 ^16.1 Hong JH et al. (2005) TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 309: 1074-8 PubMed GONUTS page

[PMID:12097321-16] Gray S et al. (2002) The Krüppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4. J Biol Chem 277: 34322-8 PubMed GONUTS page

[PMID:15728361-17] Bennett CN et al. (2005) Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A 102: 3324-9 PubMed GONUTS page

[PMID:10937998-18] Ross SE et al. (2000) Inhibition of adipogenesis by Wnt signaling. Science 289: 950-3 PubMed GONUTS page

[PMID:17905753-19] Pérez-Mancera PA et al. (2007) Adipose tissue mass is modulated by SLUG (SNAI2). Hum Mol Genet 16: 2972-86 PubMed GONUTS page

[PMID:14744933-20] Fan M et al. (2004) Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK. Genes Dev 18: 278-89 PubMed GONUTS page

[PMID:15684432-21] Makowski L et al. (2005) The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. J Biol Chem 280: 12888-95 PubMed GONUTS page

[PMID:18492766-22] 23.0 ^23.1 Wu Y & Smas CM (2008) Wdnm1-like, a new adipokine with a role in MMP-2 activation. Am J Physiol Endocrinol Metab 295: E205-15 PubMed GONUTS page

[PMID:15673614-23] Vertino AM et al. (2005) Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell 16: 2039-48 PubMed GONUTS page

[PMID:12055200-24] Bennett CN et al. (2002) Regulation of Wnt signaling during adipogenesis. J Biol Chem 277: 30998-1004 PubMed GONUTS page

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Species (Taxon ID)	Mus musculus (house mouse) (taxon:10090)
Gene Name(s)	Pparg ( synonyms: Nr1c3, PPAR-gamma, Ppar-gamma2, PPARgamma, PPARgamma2 )
Protein Name(s)	peroxisome proliferator activated receptor gamma,
External Links
MGI	MGI:97747

MGI:Pparg

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