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MGI:Pomc
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pomc ( synonyms: ACTH, adrenal corticotropic hormone, alpha-melanocyte stimulating hormone, alpha-MSH, alphaMSH, BE, beta-endorphin, beta-melanocyte stimulating hormone, beta-MSH, gamma-melanocyte stimulating hormone, gamma-MSH, POMC, Pomc-1 ) | |
| Protein Name(s) | pro-opiomelanocortin-alpha, | |
| External Links | ||
| MGI | MGI:97742 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001664 |
G-protein coupled receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005102 |
receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005179 |
hormone activity |
MGI:MGI:3511379 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005179 |
hormone activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3797314 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006091 |
generation of precursor metabolites and energy |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007218 |
neuropeptide signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0257 |
P |
From MGI |
||
| GO:0007267 |
cell-cell signaling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008217 |
regulation of blood pressure |
MGI:MGI:3608241 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88105 |
P |
From MGI |
||
| GO:0030141 |
secretory granule |
MGI:MGI:63703 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031781 |
type 3 melanocortin receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0031782 |
type 4 melanocortin receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032098 |
regulation of appetite |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032720 |
negative regulation of tumor necrosis factor production |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0033059 |
cellular pigmentation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070996 |
type 1 melanocortin receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ciais D et al. (2004) Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b. Oncogene 23: 8673-80 PubMed GONUTS page
- ↑ Lavoie PL et al. (2008) Developmental dependence on NurRE and EboxNeuro for expression of pituitary proopiomelanocortin. Mol Endocrinol 22: 1647-57 PubMed GONUTS page
- ↑ Dostanic-Larson I et al. (2005) The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation. Proc Natl Acad Sci U S A 102: 15845-50 PubMed GONUTS page
- ↑ Wilson DB & Wyatt DP (1992) Adrenocorticotropic cell distribution in adult and embryonic pituitaries of the little (lit) mutant mouse. Anat Embryol (Berl) 186: 347-53 PubMed GONUTS page
