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MGI:Polg
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Polg ( synonyms: mitochondrial DNA polymerase gamma, mitochondrial DNA polymerase-gamma, Pol gamma, Polga, polymerase gamma ) | |
| Protein Name(s) | polymerase (DNA directed), gamma, | |
| External Links | ||
| MGI | MGI:1196389 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002020 |
protease binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003887 |
DNA-directed DNA polymerase activity |
MGI:MGI:3045911 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003887 |
DNA-directed DNA polymerase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445980 |
F |
From MGI |
||
| GO:0004527 |
exonuclease activity |
MGI:MGI:3045911 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3612004 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3583846 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3584444 |
C |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:3852644 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445980 |
C |
From MGI |
||
| GO:0005743 |
mitochondrial inner membrane |
MGI:MGI:3590069 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005760 |
gamma DNA polymerase complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445980 |
C |
From MGI |
||
| GO:0006264 |
mitochondrial DNA replication |
MGI:MGI:3583846 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3584444 |
P |
From MGI |
||
| GO:0007568 |
aging |
MGI:MGI:3045911 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3046825 |
P |
From MGI |
||
| GO:0042645 |
mitochondrial nucleoid |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0090305 |
nucleic acid phosphodiester bond hydrolysis |
MGI:MGI:3045911 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Trifunovic A et al. (2004) Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417-23 PubMed GONUTS page
- ↑ Hayashi M et al. (2006) A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy. Nat Med 12: 128-32 PubMed GONUTS page
- ↑ Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
- ↑ 4.0 4.1 Hance N et al. (2005) Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. Hum Mol Genet 14: 1775-83 PubMed GONUTS page
- ↑ Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
- ↑ Da Cruz S et al. (2003) Proteomic analysis of the mouse liver mitochondrial inner membrane. J Biol Chem 278: 41566-71 PubMed GONUTS page
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