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MGI:Polb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Polb ( synonyms: Pol beta ) | |
| Protein Name(s) | polymerase (DNA directed), beta, | |
| External Links | ||
| MGI | MGI:97740 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000795 |
synaptonemal complex |
MGI:MGI:1352950 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003684 |
damaged DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003887 |
DNA-directed DNA polymerase activity |
MGI:MGI:1334987 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0003887 |
DNA-directed DNA polymerase activity |
MGI:MGI:1352950 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0003887 |
DNA-directed DNA polymerase activity |
MGI:MGI:1355147 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0003887 |
DNA-directed DNA polymerase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3573988 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005874 |
microtubule |
MGI:MGI:3573988 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005876 |
spindle microtubule |
MGI:MGI:3573988 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006260 |
DNA replication |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0235 |
P |
From MGI |
||
| GO:0006281 |
DNA repair |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0234 |
P |
From MGI |
||
| GO:0006281 |
DNA repair |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006284 |
base-excision repair |
MGI:MGI:1355147 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006284 |
base-excision repair |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006287 |
base-excision repair, gap-filling |
MGI:MGI:1334987 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006287 |
base-excision repair, gap-filling |
MGI:MGI:1352950 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006287 |
base-excision repair, gap-filling |
MGI:MGI:3045901 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006290 |
pyrimidine dimer repair |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006916 |
anti-apoptosis |
MGI:MGI:1334987 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0006974 |
response to DNA damage stimulus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008017 |
microtubule binding |
MGI:MGI:3573988 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008219 |
cell death |
MGI:MGI:1334987 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016779 |
nucleotidyltransferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0548 |
F |
From MGI |
||
| GO:0016779 |
nucleotidyltransferase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016829 |
lyase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Esposito G et al. (2000) Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally. Proc Natl Acad Sci U S A 97: 1166-71 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Ochs K et al. (1999) Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage. Cancer Res 59: 1544-51 PubMed GONUTS page
- ↑ 3.0 3.1 Pahlavani MA et al. (2000) Normal immune function in young and old DNA polymerase-beta deficient mice. Immunol Lett 72: 17-21 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Conlon KA et al. (2005) The murine DNA glycosylase NEIL2 (mNEIL2) and human DNA polymerase beta bind microtubules in situ and in vitro. DNA Repair (Amst) 4: 419-31 PubMed GONUTS page
- ↑ Parlanti E et al. (2004) Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells. DNA Repair (Amst) 3: 703-10 PubMed GONUTS page
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