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MGI:Podxl
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Podxl ( synonyms: Ly102, PC, Pclp1, podocalyxin ) | |
| Protein Name(s) | podocalyxin-like, | |
| External Links | ||
| MGI | MGI:1351317 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001726 |
ruffle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1349490 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007162 |
negative regulation of cell adhesion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620203 |
P |
From MGI |
||
| GO:0015629 |
actin cytoskeleton |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620203 |
C |
From MGI |
||
| GO:0016324 |
apical plasma membrane |
MGI:MGI:4456941 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016477 |
cell migration |
MGI:MGI:5285160 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0022408 |
negative regulation of cell-cell adhesion |
MGI:MGI:5285160 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030175 |
filopodium |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030335 |
positive regulation of cell migration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031528 |
microvillus membrane |
MGI:MGI:4456941 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0032534 |
regulation of microvillus assembly |
MGI:MGI:4456941 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0033634 |
positive regulation of cell-cell adhesion mediated by integrin |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0036057 |
slit diaphragm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_620203 |
C |
From MGI |
||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0043231 |
intracellular membrane-bounded organelle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0050900 |
leukocyte migration |
MGI:MGI:3580935 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1351317 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Hara T et al. (1999) Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region. Immunity 11: 567-78 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Nielsen JS et al. (2007) The CD34-related molecule podocalyxin is a potent inducer of microvillus formation. PLoS One 2: e237 PubMed GONUTS page
- ↑ 3.0 3.1 Hsu YH et al. (2010) Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7. Am J Pathol 176: 3050-61 PubMed GONUTS page
- ↑ Doyonnas R et al. (2005) Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. Blood 105: 4170-8 PubMed GONUTS page
