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MGI:Plp1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Plp1 ( synonyms: DM20, Plp ) | |
| Protein Name(s) | proteolipid protein (myelin) 1, | |
| External Links | ||
| MGI | MGI:97623 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005198 |
structural molecule activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3510481 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0007229 |
integrin-mediated signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008366 |
axon ensheathment |
MGI:MGI:61349 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856065 |
P |
From MGI |
||
| GO:0010001 |
glial cell differentiation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010628 |
positive regulation of gene expression |
MGI:MGI:49382 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0019911 |
structural constituent of myelin sheath |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0022010 |
central nervous system myelination |
MGI:MGI:59023 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856067 |
P |
From MGI |
||
| GO:0042552 |
myelination |
MGI:MGI:2182535 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0042552 |
myelination |
MGI:MGI:3619818 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856065 |
P |
From MGI |
||
| GO:0042552 |
myelination |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042552 |
myelination |
MGI:MGI:49382 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042759 |
long-chain fatty acid biosynthetic process |
MGI:MGI:3619818 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1856065 |
P |
From MGI |
||
| GO:0043209 |
myelin sheath |
MGI:MGI:4867628 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0043209 |
myelin sheath |
MGI:MGI:59023 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0048469 |
cell maturation |
MGI:MGI:3614301 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Castelli M et al. (2004) MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha. J Biol Chem 279: 44731-9 PubMed GONUTS page
- ↑ SIDMAN RL et al. (1964) MUTANT MICE (QUAKING AND JIMPY) WITH DEFICIENT MYELINATION IN THE CENTRAL NERVOUS SYSTEM. Science 144: 309-11 PubMed GONUTS page
- ↑ 3.0 3.1 Amiguet P et al. (1992) Purification and partial structural and functional characterization of mouse myelin/oligodendrocyte glycoprotein. J Neurochem 58: 1676-82 PubMed GONUTS page
- ↑ 4.0 4.1 Griffiths IR et al. (1990) Rumpshaker mouse: a new X-linked mutation affecting myelination: evidence for a defect in PLP expression. J Neurocytol 19: 273-83 PubMed GONUTS page
- ↑ Li S et al. (2002) Repression of myelin proteolipid protein gene expression is mediated through both general and cell type-specific negative regulatory elements in nonexpressing cells. J Neurochem 82: 159-71 PubMed GONUTS page
- ↑ 6.0 6.1 Murad S & Kishimoto Y (1975) Alpha hydroxylation of lignoceric acid to cerebronic acid during brain development. Diminished hydroxylase activity in myelin-deficient mouse mutants. J Biol Chem 250: 5841-6 PubMed GONUTS page
- ↑ Parenti R et al. (2010) Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity. Glia 58: 1594-609 PubMed GONUTS page
- ↑ Spörkel O et al. (2002) Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development. Glia 37: 19-30 PubMed GONUTS page
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