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MGI:Pln
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pln ( synonyms: PLB ) | |
| Protein Name(s) | phospholamban, | |
| External Links | ||
| MGI | MGI:97622 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0002026 |
regulation of the force of heart contraction |
MGI:MGI:1347184 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1330824 |
P |
From MGI |
||
| GO:0005246 |
calcium channel regulator activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3047017 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0496 |
C |
From MGI |
||
| GO:0006816 |
calcium ion transport |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006874 |
cellular calcium ion homeostasis |
MGI:MGI:1347184 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88110 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016529 |
sarcoplasmic reticulum |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016529 |
sarcoplasmic reticulum |
MGI:MGI:85770 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031982 |
vesicle |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042030 |
ATPase inhibitor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045822 |
negative regulation of heart contraction |
MGI:MGI:1347184 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88110 |
P |
From MGI |
||
| GO:0048738 |
cardiac muscle tissue development |
MGI:MGI:1347184 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1330824 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Minamisawa S et al. (1999) Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell 99: 313-22 PubMed GONUTS page
- ↑ Asahi M et al. (2004) Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice. Proc Natl Acad Sci U S A 101: 9199-204 PubMed GONUTS page
- ↑ Harrer JM et al. (1997) Coordinate regulation of SR Ca(2+)-ATPase and phospholamban expression in developing murine heart. Am J Physiol 272: H57-66 PubMed GONUTS page
ac |
imnp |
p cont.rsv |
