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MGI:Plg

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Plg ( synonyms: Pg )
Protein Name(s) plasminogen,
External Links
MGI MGI:97620

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009003

F

From MGI

GO:0004175

endopeptidase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q01177

F

From MGI

GO:0004252

serine-type endopeptidase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

C

From MGI

GO:0005792

microsome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q01177

C

From MGI

GO:0006508

proteolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018114
InterPro:IPR001254
InterPro:IPR001314

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:2386151
PMID:12167431[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006917

induction of apoptosis

MGI:MGI:2386151
PMID:12167431[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007596

blood coagulation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

P

From MGI

GO:0007599

hemostasis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0356

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

From MGI

GO:0008236

serine-type peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0720

F

From MGI

GO:0010812

negative regulation of cell-substrate adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

P

From MGI

GO:0016525

negative regulation of angiogenesis

MGI:MGI:2386151
PMID:12167431[1]

TAS: Traceable Author Statement

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0019897

extrinsic to plasma membrane

MGI:MGI:3847621
PMID:17690254[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0019904

protein domain specific binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

F

From MGI

GO:0022617

extracellular matrix disassembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

P

From MGI

GO:0031232

extrinsic to external side of plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

C

From MGI

GO:0034185

apolipoprotein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

F

From MGI

GO:0042246

tissue regeneration

MGI:MGI:2178512
PMID:11929773[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2158761

P

From MGI

GO:0042730

fibrinolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0280

P

From MGI

GO:0043498

cell surface binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

F

From MGI

GO:0045445

myoblast differentiation

MGI:MGI:2178512
PMID:11929773[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046716

muscle cell homeostasis

MGI:MGI:2178512
PMID:11929773[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2158761

P

From MGI

GO:0048771

tissue remodeling

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0797

P

From MGI

GO:0051603

proteolysis involved in cellular protein catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q01177

P

From MGI

GO:0051918

negative regulation of fibrinolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

P

From MGI

GO:0051919

positive regulation of fibrinolysis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00747

P

From MGI

GO:0060707

trophoblast giant cell differentiation

MGI:MGI:2668370
PMID:12900459[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857291

P

From MGI

GO:0060716

labyrinthine layer blood vessel development

MGI:MGI:2668370
PMID:12900459[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857291

P

From MGI

GO:0071674

mononuclear cell migration

MGI:MGI:3847621
PMID:17690254[2]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Matsumoto G et al. (2002) Growth of human squamous cell carcinoma xenografts in mice is inhibited by local angiostatin gene therapy. Oral Oncol 38: 543-8 PubMed GONUTS page
  2. 2.0 2.1 Das R et al. (2007) Histone H2B as a functionally important plasminogen receptor on macrophages. Blood 110: 3763-72 PubMed GONUTS page
  3. 3.0 3.1 3.2 Suelves M et al. (2002) Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo. Blood 99: 2835-44 PubMed GONUTS page
  4. 4.0 4.1 Solberg H et al. (2003) A functional overlap of plasminogen and MMPs regulates vascularization during placental development. Development 130: 4439-50 PubMed GONUTS page
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