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MGI:Plek
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Plek | |
| Protein Name(s) | pleckstrin, | |
| External Links | ||
| MGI | MGI:1860485 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005080 |
protein kinase C binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005625 |
soluble fraction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006904 |
vesicle docking involved in exocytosis |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007229 |
integrin-mediated signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010572 |
positive regulation of platelet activation |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0010920 |
negative regulation of inositol phosphate biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010925 |
positive regulation of inositol-polyphosphate 5-phosphatase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030030 |
cell projection organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030836 |
positive regulation of actin filament depolymerization |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030836 |
positive regulation of actin filament depolymerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030845 |
inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030866 |
cortical actin cytoskeleton organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031529 |
ruffle organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031532 |
actin cytoskeleton reorganization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032233 |
positive regulation of actin filament bundle assembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032587 |
ruffle membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0033625 |
positive regulation of integrin activation |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0035556 |
intracellular signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043325 |
phosphatidylinositol-3,4-bisphosphate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045744 |
negative regulation of G-protein coupled receptor protein signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046488 |
phosphatidylinositol metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0060305 |
regulation of cell diameter |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070493 |
thrombin receptor signaling pathway |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070493 |
thrombin receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070527 |
platelet aggregation |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070528 |
protein kinase C signaling cascade |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0070560 |
protein secretion by platelet |
MGI:MGI:3844782 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Lian L et al. (2009) Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis. Blood 113: 3577-84 PubMed GONUTS page
