Have any questions? Please email us at ecoliwiki@gmail.com

MGI:Pld2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pld2
Protein Name(s) phospholipase D2,
External Links
MGI MGI:892877

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0030335

positive regulation of cell migration

PMID:20647543[1]

IMP: Inferred from Mutant Phenotype

P

Figure 3A: Showed silencing of PLD2 significantly decreased cell migration. Figure 3C: Showed that over expression of PLD2 increases cell migration.

complete

GO:0001666

response to hypoxia

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0002031

G-protein coupled receptor internalization

MGI:MGI:3042801
PMID:14718562[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001736

F

From MGI

GO:0004630

phospholipase D activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

F

From MGI

GO:0005543

phospholipid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001849

F

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:3042801
PMID:14718562[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

C

From MGI

GO:0005901

caveola

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

C

From MGI

GO:0006629

lipid metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0443

P

From MGI

GO:0006898

receptor-mediated endocytosis

MGI:MGI:3042801
PMID:14718562[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007154

cell communication

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001683

P

From MGI

GO:0008152

metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001736

P

From MGI

GO:0009395

phospholipid catabolic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0014068

positive regulation of phosphatidylinositol 3-kinase cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0014070

response to organic cyclic compound

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016042

lipid catabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0442

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0030027

lamellipodium

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

C

From MGI

GO:0030335

positive regulation of cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0031175

neuron projection development

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0031526

brush border membrane

MGI:MGI:3526585
PMID:15598876[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0035091

phosphatidylinositol binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001683

F

From MGI

GO:0042383

sarcolemma

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

C

From MGI

GO:0042542

response to hydrogen peroxide

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0042802

identical protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O14939

F

From MGI

GO:0043306

positive regulation of mast cell degranulation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0043434

response to peptide hormone stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0045785

positive regulation of cell adhesion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0048260

positive regulation of receptor-mediated endocytosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P70498

P

From MGI

GO:0070290

NAPE-specific phospholipase D activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:3.1.4.4

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Knapek, K et al. (2010) The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts. Mol. Cell. Biol. 30 4492-506 PubMed GONUTS page
  2. 2.0 2.1 2.2 Du, G et al. (2004) Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis. Mol. Biol. Cell 15 1024-30 PubMed GONUTS page
  3. Yang, Z et al. (2005) D5 dopamine receptor regulation of phospholipase D. Am. J. Physiol. Heart Circ. Physiol. 288 H55-61 PubMed GONUTS page
<protect>