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MGI:Plau

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Plau ( synonyms: u-PA, uPA, urokinase-type plasminogen activator )
Protein Name(s) plasminogen activator, urokinase,
External Links
MGI MGI:97611

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001525

angiogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29598

P

From MGI

GO:0001666

response to hypoxia

MGI:MGI:3721729
PMID:17382917[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009003

F

From MGI

GO:0004252

serine-type endopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018114
InterPro:IPR001254
InterPro:IPR001314

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00749

C

From MGI

GO:0006508

proteolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

P

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR018114
InterPro:IPR001254
InterPro:IPR001314

P

From MGI

GO:0008233

peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0645

F

From MGI

GO:0008236

serine-type peptidase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0720

F

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00749

C

From MGI

GO:0010469

regulation of receptor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00749

P

From MGI

GO:0014909

smooth muscle cell migration

MGI:MGI:3721729
PMID:17382917[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0014910

regulation of smooth muscle cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00749

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0033628

regulation of cell adhesion mediated by integrin

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00749

P

From MGI

GO:0042060

wound healing

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29598

P

From MGI

GO:0042127

regulation of cell proliferation

MGI:MGI:3762318
PMID:17893885[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:88039

P

From MGI

GO:0043403

skeletal muscle tissue regeneration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P29598

P

From MGI

GO:2000097

regulation of smooth muscle cell-matrix adhesion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P00749

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Hou Y et al. (2007) c-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells. Cardiovasc Res 75: 186-94 PubMed GONUTS page
  2. Ploplis VA et al. (2007) A urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ mice. J Pathol 213: 266-74 PubMed GONUTS page
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