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MGI:Pla2r1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pla2r1 ( synonyms: M-type receptor, PLA2-I receptor, Pla2g1br ) | |
| Protein Name(s) | phospholipase A2 receptor 1, | |
| External Links | ||
| MGI | MGI:102468 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001816 |
cytokine production |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:78038 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:5297792 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006897 |
endocytosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0254 |
P |
From MGI |
||
| GO:0006898 |
receptor-mediated endocytosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006898 |
receptor-mediated endocytosis |
MGI:MGI:68989 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0030246 |
carbohydrate binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0043274 |
phospholipase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043274 |
phospholipase binding |
MGI:MGI:5297792 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0043274 |
phospholipase binding |
MGI:MGI:68989 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0043517 |
positive regulation of DNA damage response, signal transduction by p53 class mediator |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0072593 |
reactive oxygen species metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090238 |
positive regulation of arachidonic acid secretion |
MGI:MGI:5297793 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090399 |
replicative senescence |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090403 |
oxidative stress-induced premature senescence |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:1900138 |
negative regulation of phospholipase A2 activity |
MGI:MGI:5297792 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:1900139 |
negative regulation of arachidonic acid secretion |
MGI:MGI:5297792 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zvaritch E et al. (1996) Endocytic properties of the M-type 180-kDa receptor for secretory phospholipases A2. J Biol Chem 271: 250-7 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Higashino Ki K et al. (2002) Identification of a soluble form phospholipase A2 receptor as a circulating endogenous inhibitor for secretory phospholipase A2. J Biol Chem 277: 13583-8 PubMed GONUTS page
- ↑ 3.0 3.1 Higashino K et al. (1994) Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals. Eur J Biochem 225: 375-82 PubMed GONUTS page
- ↑ Fonteh AN et al. (2000) Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells. J Immunol 165: 2773-82 PubMed GONUTS page
