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MGI:Pla2g10
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pla2g10 ( synonyms: GX sPLA2, mGXsPLA2, PLA2GX ) | |
| Protein Name(s) | phospholipase A2, group X, | |
| External Links | ||
| MGI | MGI:1347522 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004620 |
phospholipase activity |
MGI:MGI:5051938 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0004623 |
phospholipase A2 activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_058872 |
F |
From MGI |
||
| GO:0005509 |
calcium ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0006644 |
phospholipid metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007411 |
axon guidance |
MGI:MGI:3589698 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010884 |
positive regulation of lipid storage |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016042 |
lipid catabolic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0442 |
P |
From MGI |
||
| GO:0016042 |
lipid catabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016787 |
hydrolase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0378 |
F |
From MGI |
||
| GO:0032270 |
positive regulation of cellular protein metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0032308 |
positive regulation of prostaglandin secretion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042632 |
cholesterol homeostasis |
MGI:MGI:5051938 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043030 |
regulation of macrophage activation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
MGI:MGI:5051938 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051977 |
lysophospholipid transport |
MGI:MGI:3589698 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090238 |
positive regulation of arachidonic acid secretion |
MGI:MGI:5051938 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0090370 |
negative regulation of cholesterol efflux |
MGI:MGI:5051938 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Shridas P et al. (2010) Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages. Arterioscler Thromb Vasc Biol 30: 2014-21 PubMed GONUTS page
- ↑ 2.0 2.1 Ikeno Y et al. (2005) Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor. J Biol Chem 280: 28044-52 PubMed GONUTS page
