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MGI:Pknox2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pknox2 ( synonyms: Prep2 )
Protein Name(s) Pbx/knotted 1 homeobox 2,
External Links
MGI MGI:2445415

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:2429830
PMID:12412021[1]

ISA: Inferred from Sequence Alignment

UniProtKB:Q96KN3

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From MGI

GO:0003785

actin monomer binding

MGI:MGI:3522406
PMID:15339927[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005634

nucleus

MGI:MGI:3522406
PMID:15339927[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:3703117
PMID:17049510[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:2429830
PMID:12412021[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008422
InterPro:IPR001356

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:3703117
PMID:17049510[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97495

P

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:3522406
PMID:15339927[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0015630

microtubule cytoskeleton

MGI:MGI:3522406
PMID:15339927[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:3653971
PMID:16847320[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:3703117
PMID:17049510[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97495

F

From MGI

GO:0051015

actin filament binding

MGI:MGI:3522406
PMID:15339927[2]

IDA: Inferred from Direct Assay

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Haller K et al. (2002) Prep2: cloning and expression of a new prep family member. Dev Dyn 225: 358-64 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Haller K et al. (2004) Subcellular localization of multiple PREP2 isoforms is regulated by actin, tubulin, and nuclear export. J Biol Chem 279: 49384-94 PubMed GONUTS page
  3. 3.0 3.1 3.2 Zhang X et al. (2006) Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development. Dev Biol 300: 748-57 PubMed GONUTS page
  4. Ferretti E et al. (2006) Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol Cell Biol 26: 5650-62 PubMed GONUTS page
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