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MGI:Pkd2l1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Pkd2l1 ( synonyms: PCL, PKD2L, Pkdl, polycystin-L, TRPP3 ) | |
| Protein Name(s) | polycystic kidney disease 2-like 1, | |
| External Links | ||
| MGI | MGI:1352448 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001581 |
detection of chemical stimulus involved in sensory perception of sour taste |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0005227 |
calcium activated cation channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005261 |
cation channel activity |
MGI:MGI:3573990 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005261 |
cation channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005272 |
sodium channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005509 |
calcium ion binding |
MGI:MGI:5315681 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3573990 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5315344 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:3573990 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3573990 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006812 |
cation transport |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008092 |
cytoskeletal protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015269 |
calcium-activated potassium channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035725 |
sodium ion transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:5315681 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0043231 |
intracellular membrane-bounded organelle |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0051371 |
muscle alpha-actinin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051393 |
alpha-actinin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051925 |
regulation of calcium ion transport via voltage-gated calcium channel activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071468 |
cellular response to acidity |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071805 |
potassium ion transmembrane transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
colocalizes_with |
GO:0009986 |
cell surface |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
C |
From MGI |
||
|
contributes_to |
GO:0005261 |
cation channel activity |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
F |
From MGI |
||
|
contributes_to |
GO:0008324 |
cation transmembrane transporter activity |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
F |
From MGI |
||
|
contributes_to |
GO:0033040 |
sour taste receptor activity |
MGI:MGI:5315344 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Ishimaru Y et al. (2006) Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. Proc Natl Acad Sci U S A 103: 12569-74 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Murakami M et al. (2005) Genomic organization and functional analysis of murine PKD2L1. J Biol Chem 280: 5626-35 PubMed GONUTS page
- ↑ 3.0 3.1 Molland KL et al. (2010) Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2. Biochem J 429: 171-83 PubMed GONUTS page
