GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Piwil4
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Piwil4 ( synonyms: MIWI2 ) | |
| Protein Name(s) | piwi-like homolog 4 (Drosophila), | |
| External Links | ||
| MGI | MGI:3041167 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003676 |
nucleic acid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003723 |
RNA binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0694 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:3655410 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4418580 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3815367 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3815367 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006417 |
regulation of translation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0810 |
P |
From MGI |
||
| GO:0007126 |
meiosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0469 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:3708051 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:3778312 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0031047 |
gene silencing by RNA |
MGI:MGI:3708051 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031047 |
gene silencing by RNA |
MGI:MGI:3778312 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0031047 |
gene silencing by RNA |
MGI:MGI:3815367 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034584 |
piRNA binding |
MGI:MGI:3815367 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0034587 |
piRNA metabolic process |
MGI:MGI:3708051 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034587 |
piRNA metabolic process |
MGI:MGI:3778312 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0034587 |
piRNA metabolic process |
MGI:MGI:3815367 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043046 |
DNA methylation involved in gamete generation |
MGI:MGI:3778312 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043046 |
DNA methylation involved in gamete generation |
MGI:MGI:3815367 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043186 |
P granule |
MGI:MGI:3815367 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0071547 |
piP-body |
MGI:MGI:4417983 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0071547 |
piP-body |
MGI:MGI:4418580 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Costa Y et al. (2006) Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway? Hum Mol Genet 15: 2324-34 PubMed GONUTS page
- ↑ 2.0 2.1 Shoji M et al. (2009) The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell 17: 775-87 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Aravin AA et al. (2008) A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell 31: 785-99 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Carmell MA et al. (2007) MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 12: 503-14 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Kuramochi-Miyagawa S et al. (2008) DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev 22: 908-17 PubMed GONUTS page
- ↑ Aravin AA et al. (2009) Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet 5: e1000764 PubMed GONUTS page
cdgm |
np |
p cont.rs |
