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MGI:Pip5k3

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Mus musculus (house mouse)

Pip5k3:phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
Synonyms:Pikfyve
Pip5k3 on MGI

GO terms

GO:0005515_!_protein_binding (F) IPI with/from UniProtKB:Q92562 [1]
GO:0005524_!_ATP_binding (F) IEA with/from InterPro:IPR002423 [2]
GO:0005829_!_cytosol (C) IDA [3]
GO:0007242_!_intracellular_signaling_cascade (P) IDA [4]
GO:0008270_!_zinc_ion_binding (F) IDA [4]
GO:0016020_!_membrane (C) IEA with/from SP_KW:KW-0472 [5]
GO:0016301_!_kinase_activity (F) IEA with/from SP_KW:KW-0418 [5]
GO:0016307_!_phosphatidylinositol_phosphate_kinase_activity (F) IEA with/from InterPro:IPR002498 [2]
GO:0016308_!_1-phosphatidylinositol-4-phosphate_5-kinase_activity (F) IDA [4]
GO:0016740_!_transferase_activity (F) IEA with/from SP_KW:KW-0808 [5]
GO:0031410_!_cytoplasmic_vesicle (C) IDA [3]
GO:0044267_!_cellular_protein_metabolic_process (P) IEA with/from InterPro:IPR002423 [2]
GO:0046488_!_phosphatidylinositol_metabolic_process (P) IEA with/from InterPro:IPR002498 [2]
GO:0046872_!_metal_ion_binding (F) IEA with/from SP_KW:KW-0479 [5]
NOT GO:0032593_!_insulin-responsive_compartment (C) IDA [3]

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Notes

References

See Help:References for how to manage references in GONUTS.
  1. Sbrissa D et al. (2007) Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex. J Biol Chem 282: 23878-91 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 MGI annotation MGI:2152098
  3. 3.0 3.1 3.2 Shisheva A et al. (2001) Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes. J Biol Chem 276: 11859-69 PubMed GONUTS page
  4. 4.0 4.1 4.2 Shisheva A et al. (1999) Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells. Mol Cell Biol 19: 623-34 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 MGI annotation MGI:1354194
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