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MGI:Pick1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Pick1 ( synonyms: Prkcabp )
Protein Name(s) protein interacting with C kinase 1,
External Links
MGI MGI:894645

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005080

protein kinase C binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

F

From MGI

GO:0005080

protein kinase C binding

MGI:MGI:893264
PMID:7844141[1]

IPI: Inferred from Physical Interaction

UniProtKB:P04409

F

From MGI

GO:0005102

receptor binding

MGI:MGI:1327089
PMID:9883737[2]

IPI: Inferred from Physical Interaction

UniProtKB:P54759
UniProtKB:P54763

F

From MGI

GO:0005102

receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

F

From MGI

GO:0005515

protein binding

MGI:MGI:1327089
PMID:9883737[2]

IPI: Inferred from Physical Interaction

UniProtKB:P98172

F

From MGI

GO:0005622

intracellular

MGI:MGI:893264
PMID:7844141[1]

NAS: Non-traceable Author Statement

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:893264
PMID:7844141[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:2675925
PMID:12826667[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:893264
PMID:7844141[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

C

From MGI

GO:0006200

ATP catabolic process

MGI:MGI:3700424
PMID:11931741[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

P

From MGI

GO:0006605

protein targeting

MGI:MGI:2675925
PMID:12826667[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007205

activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

P

From MGI

GO:0007243

intracellular protein kinase cascade

MGI:MGI:893264
PMID:7844141[1]

NAS: Non-traceable Author Statement

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1327089
PMID:9883737[2]

NAS: Non-traceable Author Statement

P

From MGI

GO:0008022

protein C-terminus binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

F

From MGI

GO:0008022

protein C-terminus binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

F

From MGI

GO:0014069

postsynaptic density

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

C

From MGI

GO:0015844

monoamine transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

P

From MGI

GO:0016887

ATPase activity

MGI:MGI:3700424
PMID:11931741[4]

IDA: Inferred from Direct Assay

F

From MGI

GO:0019717

synaptosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

C

From MGI

GO:0019899

enzyme binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

F

From MGI

GO:0019904

protein domain specific binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

F

From MGI

GO:0030054

cell junction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From MGI

GO:0030425

dendrite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

C

From MGI

GO:0042734

presynaptic membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9NRD5

C

From MGI

GO:0042802

identical protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

F

From MGI

GO:0043113

receptor clustering

MGI:MGI:1327089
PMID:9883737[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043113

receptor clustering

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

P

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

C

From MGI

GO:0045202

synapse

MGI:MGI:1327089
PMID:9883737[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0045202

synapse

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

C

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_445912

C

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:893264
PMID:7844141[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0050803

regulation of synapse structure and activity

MGI:MGI:1327089
PMID:9883737[2]

NAS: Non-traceable Author Statement

P

From MGI

GO:0051260

protein homooligomerization

MGI:MGI:3687711
PMID:9405395[5]

TAS: Traceable Author Statement

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Staudinger J et al. (1995) PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol 128: 263-71 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Torres R et al. (1998) PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron 21: 1453-63 PubMed GONUTS page
  3. 3.0 3.1 Wang WL et al. (2003) PICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cells. J Biol Chem 278: 37705-12 PubMed GONUTS page
  4. 4.0 4.1 Hanley JG et al. (2002) NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex. Neuron 34: 53-67 PubMed GONUTS page
  5. Staudinger J et al. (1997) Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha. J Biol Chem 272: 32019-24 PubMed GONUTS page
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