Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Picalm

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Picalm ( synonyms: fit-1, fit1 )
Protein Name(s) phosphatidylinositol binding clathrin assembly protein,
External Links
MGI MGI:2385902

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005543

phospholipid binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011417

F

From MGI

GO:0005545

1-phosphatidylinositol binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

F

From MGI

GO:0005622

intracellular

MGI:MGI:4418607
PMID:18842885[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

C

From MGI

GO:0005768

endosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0333

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0005905

coated pit

MGI:MGI:2667577
PMID:12832620[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005905

coated pit

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

C

From MGI

GO:0006897

endocytosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0254

P

From MGI

GO:0006898

receptor-mediated endocytosis

MGI:MGI:2667577
PMID:12832620[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006898

receptor-mediated endocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007409

axonogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

P

From MGI

GO:0007409

axonogenesis

MGI:MGI:4418607
PMID:18842885[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0008021

synaptic vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0014069

postsynaptic density

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016192

vesicle-mediated transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

P

From MGI

GO:0016197

endosome transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0017124

SH3 domain binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

F

From MGI

GO:0030097

hemopoiesis

MGI:MGI:2667577
PMID:12832620[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030100

regulation of endocytosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

P

From MGI

GO:0030100

regulation of endocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0030118

clathrin coat

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR014712

C

From MGI

GO:0030136

clathrin-coated vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0030276

clathrin binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

F

From MGI

GO:0030276

clathrin binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

F

From MGI

GO:0031410

cytoplasmic vesicle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0968

C

From MGI

GO:0031623

receptor internalization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0032050

clathrin heavy chain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

F

From MGI

GO:0032880

regulation of protein localization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0042734

presynaptic membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0042802

identical protein binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

F

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:E9PN05

C

From MGI

GO:0045202

synapse

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0045211

postsynaptic membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

C

From MGI

GO:0045893

positive regulation of transcription, DNA-dependent

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0048261

negative regulation of receptor-mediated endocytosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0048268

clathrin coat assembly

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

P

From MGI

GO:0048268

clathrin coat assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13492

P

From MGI

GO:0048813

dendrite morphogenesis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

P

From MGI

GO:0048813

dendrite morphogenesis

MGI:MGI:4418607
PMID:18842885[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0051223

regulation of protein transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:O55012

P

From MGI

colocalizes_with

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4410429
PMID:18182011[3]

IDA: Inferred from Direct Assay

C

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Bushlin I et al. (2008) Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons. J Neurosci 28: 10257-71 PubMed GONUTS page
  2. 2.0 2.1 2.2 Klebig ML et al. (2003) Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice. Proc Natl Acad Sci U S A 100: 8360-5 PubMed GONUTS page
  3. Harel A et al. (2008) Evidence for CALM in directing VAMP2 trafficking. Traffic 9: 417-29 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox