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MGI:Phip

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Phip ( synonyms: Ndrp, Wdr11 )
Protein Name(s) pleckstrin homology domain interacting protein,
External Links
MGI MGI:1932404

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003674

molecular function

MGI:MGI:2156816

ND: No biological Data available

F

From MGI

GO:0005622

intracellular

MGI:MGI:4833711
PMID:20816727[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4129907

C

From MGI

GO:0005634

nucleus

MGI:MGI:3723572
PMID:17636024[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006606

protein import into nucleus

MGI:MGI:4833711
PMID:20816727[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4129907

P

From MGI

GO:0007010

cytoskeleton organization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WWQ0

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:3723572
PMID:17636024[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:109334
MGI:MGI:96432

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4833711
PMID:20816727[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4129907

P

From MGI

GO:0008286

insulin receptor signaling pathway

MGI:MGI:1928448
PMID:11018022[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

MGI:MGI:3723572
PMID:17636024[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0022604

regulation of cell morphogenesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8WWQ0

P

From MGI

GO:0033138

positive regulation of peptidyl-serine phosphorylation

MGI:MGI:3723572
PMID:17636024[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0040008

regulation of growth

MGI:MGI:4833711
PMID:20816727[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:4129907

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:3723572
PMID:17636024[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3723572
PMID:17636024[2]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Li S et al. (2010) The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth. FEBS Lett 584: 4121-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Podcheko A et al. (2007) Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival. Mol Cell Biol 27: 6484-96 PubMed GONUTS page
  3. Farhang-Fallah J et al. (2000) Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting protein. J Biol Chem 275: 40492-7 PubMed GONUTS page
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