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MGI:Phgdh
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Phgdh ( synonyms: 3-PGDH, 3PGDH, A10, PGAD, PGD, PGDH, SERA ) | |
| Protein Name(s) | 3-phosphoglycerate dehydrogenase, | |
| External Links | ||
| MGI | MGI:1355330 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004617 |
phosphoglycerate dehydrogenase activity |
MGI:MGI:2150504 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0004617 |
phosphoglycerate dehydrogenase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0006541 |
glutamine metabolic process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0006544 |
glycine metabolic process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0006563 |
L-serine metabolic process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0006564 |
L-serine biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0718 |
P |
From MGI |
||
| GO:0006564 |
L-serine biosynthetic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006566 |
threonine metabolic process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008652 |
cellular amino acid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0028 |
P |
From MGI |
||
| GO:0009448 |
gamma-aminobutyric acid metabolic process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0010468 |
regulation of gene expression |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0019530 |
taurine metabolic process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0021510 |
spinal cord development |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0021782 |
glial cell development |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0021915 |
neural tube development |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0022008 |
neurogenesis |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0022402 |
cell cycle process |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0031175 |
neuron projection development |
MGI:MGI:3835979 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3769591 |
P |
From MGI |
||
| GO:0048037 |
cofactor binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0051287 |
NAD binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yamasaki M et al. (2001) 3-Phosphoglycerate dehydrogenase, a key enzyme for l-serine biosynthesis, is preferentially expressed in the radial glia/astrocyte lineage and olfactory ensheathing glia in the mouse brain. J Neurosci 21: 7691-704 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 Kawakami Y et al. (2009) Impaired neurogenesis in embryonic spinal cord of Phgdh knockout mice, a serine deficiency disorder model. Neurosci Res 63: 184-93 PubMed GONUTS page
