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MGI:Peli1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Peli1 ( synonyms: D11Ertd676e ) | |
| Protein Name(s) | pellino 1, | |
| External Links | ||
| MGI | MGI:1914495 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000209 |
protein polyubiquitination |
MGI:MGI:5291872 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0001819 |
positive regulation of cytokine production |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:4359971 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
MGI:MGI:5291872 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4359971 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5291872 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:5291872 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016874 |
ligase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0436 |
F |
From MGI |
||
| GO:0030890 |
positive regulation of B cell proliferation |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0031398 |
positive regulation of protein ubiquitination |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
MGI:MGI:5291872 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0032496 |
response to lipopolysaccharide |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0034141 |
positive regulation of toll-like receptor 3 signaling pathway |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0034145 |
positive regulation of toll-like receptor 4 signaling pathway |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0042130 |
negative regulation of T cell proliferation |
MGI:MGI:5291872 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0043331 |
response to dsRNA |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0050868 |
negative regulation of T cell activation |
MGI:MGI:5291872 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0050871 |
positive regulation of B cell activation |
MGI:MGI:4359971 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:4361448 |
P |
From MGI |
||
| GO:0070936 |
protein K48-linked ubiquitination |
MGI:MGI:5291872 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Chang M et al. (2011) The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nat Immunol 12: 1002-9 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 Chang M et al. (2009) Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Nat Immunol 10: 1089-95 PubMed GONUTS page
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